脑梗死危险因素及生化特征分析  

Risk factors and biochemical indicators of cerebral infarction

作　　者：吴金飞[1] 陈传琳 曾素琴[1] 熊宁[1] 

机构地区：[1]解放军184医院心脑血管科,江西鹰潭335000

出　　处：《东南国防医药》2014年第3期270-272,共3页Military Medical Journal of Southeast China

摘　　要：目的探讨脑梗死发病的危险因素及生化指标特征。方法采用回顾性调查方法,将调查对象分为脑梗死组(165例)与对照组(66例),通过Logistic回归分析、t检验方法对数据进行处理。结果单因素Logistic回归分析中,年龄、吸烟史、高血压史、糖尿病史与脑梗死发病密切相关(P<0.05);组间比较t检验分析中,急性期脑梗死组白细胞计数高于非急性期组对照组(P<0.05),脑梗死患者中性粒细胞百分比、C反应蛋白、转脂蛋白a、总胆固醇、低密度脂蛋白胆固醇、血糖均高于对照组(P<0.05)。结论血脂、血糖、血压异常增高及吸烟是导致发病的确切危险因素,脑梗死病变初期伴明显的炎性反应,倡导健康的饮食、生活习惯及对血压、血糖、血脂的管理有助于预防脑梗死的发病,脑梗死发病初期需积极抑制炎性反应。Objective To explore risk factors ,biochemical indicators of cerebral infarction .Methods A retrospective analy-sis including 165 patients with cerebral infarction divided into acute group and non-acute group and 66 control subjects were carried out.The descriptive statistics,t test were used in the study of biochemical indicators of cerebral infarction ,logistic regression analysis were used in the study for comparing the risk factors .Results According to the results of single-factor logistic regression analysis ,sex, age,smoking history,hypertension history,diabetes were closely correlated with the occurrence of cerebral infarction （P〈0.05）.According to the results of t test ,the WBC of patients with cerebral infarction in acute group was significant higher than WBC of patients in non-acute group and control group （P〈0.05）.The percentage of GRAN,and levels of CRP,LPA,TC,LDL-C and GLU of patients with cerebral infarction were significant higher than that of patients in the control group （P〈0.05）.Conclusion Abnormal blood lipids, increased blood glucose level ,increased blood pressure and the smoking were confirmed risk factors of cerebral infarction ,the inflamma-tory reaction during initial stage of cerebral infarction ,reasonable diet ,healthy life style as well as the good management of the underly-ing disease were significant measures for prevention of cerebral infarction .On the early stage of cerebral infarction should inhibit the in-flammatory reaction .

关 键 词：脑梗死 危险因素 生化特征 

分 类 号：R681[医药卫生—骨科学]