选择性痔上黏膜切除术治疗混合痔60例随机单盲对照临床试验  

Clinical study of tissue-selecting therapy in the treatment of mixed hemorrhoids： a single-blind randomized controlled trail

作　　者：何红艳[1] 贺平[1] 刘宁[1] 

机构地区：[1]成都肛肠专科医院肛肠科,610015

出　　处：《中华胃肠外科杂志》2014年第6期586-588,共3页Chinese Journal of Gastrointestinal Surgery

摘　　要：目的观察和评价选择性痔上黏膜切除术（偈T）治疗混合痔的临床疗效及安全性。方法前瞻性将2012年1—12月期间成都肛肠专科医院收治的120例混合痔患者按随机序列表法分成两组，每组60例，分别行＇rST（治疗组）和吻合器痔上黏膜环切钉合术（对照组）。观察对比两组患者的手术情况以及临床疗效和术后并发症。结果两组患者均顺利完成手术。治疗组与对照组相比，手术时间较短[（15．9±5．2）min比（22．6±7．1）min，P〈0．05]，出院时肛门坠胀评分较低[（0．5±0．2）分比（1．5±1．4）分，P〈0．05]，住院天数较短[（11．2±3．7）d比（14．8±3．7）d，P〈0．05]；治疗组术后无发生吻合口狭窄者，而对照组有11例（18．3％，P〈0．05）。但两组术后第1次排粪时疼痛评分和治疗有效率的差异均无统计学意义（P〉0．05）。结论11sT术治疗混合痔操作简单，疗效确切，术后患者恢复快，并发症少。Objective To evaluate the clinical efficacy and safety of tissue-selecting therapy （TST） in treatment of mixed hemorrhoids. Methods A single-blind randomized study was carried out. A total of 120 patients with mixed hemorrhoids from January to December 2012 were prospectively enrolled in the study and equally divided into two groups, TST group and procedure for prolapse and hemorrhoids （PPH） group. Surgical data, efficacy and postoperative complications were compared between the two groups. Results As compared to PPH group, patients in TST group had shorter operation time [ （15.9±5.18） min vs. （22.6±7.1） min, P〈0.05], lower scores of rectal urgency （0.5± 0.2 vs. 1.5±1.4, P〈0.05）, and shorter hospital stay [（11.2±3.7） d vs. （14.8±3.7） d, P〈0.05]. No anastomotic stricture case was found in TST group, while 11 cases （18.3%） developed anastomotic stricture in PPH group. There were no significant differences in effective rate and pain score of first defecation between the two groups. Conclusion TST is reliable and safe for mixed hemorrhoids with the advantage of simple, rapid recovery and less complications.

关 键 词：混合痔 选择性痔上黏膜切除术 痔上黏膜环切钉合术 临床研究 

分 类 号：R657.18[医药卫生—外科学]