液基细胞制片在甲状腺结节诊断中的应用价值  

Application value of liquid-based cytology test in diagnosis of thyroid nodule

作　　者：杨汶士[1] 邹汉青[1] 徐龙江[1] 金涛[1] 朱培培[1] 洪荫[1] 王亮[1] 王国强[1] 朱旬[1] 

机构地区：[1]苏州大学附属第二医院普通外科,215004

出　　处：《江苏医药》2014年第11期1315-1317,共3页Jiangsu Medical Journal

摘　　要：目的探讨液基细胞制片对提高甲状腺结节诊断准确率的应用价值。方法 81例甲状腺结节患者术前细针穿刺(FNA)甲状腺结节,穿刺物分别采用液基细胞制片与传统涂片制片技术处理,以组织病理学诊断为金标准分析两种制片方法的诊断准确率。结果液基细胞制片诊断准确率为92.59%(75/81),高于传统涂片制片的86.42%(70/81)(P<0.05)。液基细胞制片诊断敏感性和特异性分别为85.00%和95.08%,均高于传统制片技术的75.00%和90.16%)(P<0.01)。结论液基细胞制片能有效提高甲状腺FNA涂片质量和术前诊断准确率。Objective To explore the value of liquid-based cytology test in the diagnosis of thyroid nodule. Methods Fine-needle aspiration（FNA） was conducted in 81 patients with thyroid nodules before operation. A total of 81 specimen was prepared by liquid-based cytology test（group A） and conventional smear technique（group B）, respectively. Taking histopathological diagnosis as golden standard, the accuracy rates of diagnosis were compared between two groups. Results The accuracy rate of diagnosis was higher in group A than that in group B（92. 59% vs. 86.42%）（P〈0. 05）. The sensitivity and specificity of group A were 85.00% and 95. 08% ,which were higher than 75.00% and 90.16% of group B（P〈0. 01）. Conclusion liquid-based cytology test can effectively improve the smear quality of FNA and preoperative diagnostic accuracy.

关 键 词：甲状腺结节 液基细胞制片 细针穿刺 

分 类 号：R446[医药卫生—诊断学]