N取代吩噻嗪衍生物的合成及其铜离子传感性能  

Synthesis of a N-substituted Phenothiazine Derivative and its Sensor Property for Cu(2+)

作　　者：张曼[1] 马鹏[1] 童碧海[1] 张千峰[1] 

机构地区：[1]安徽工业大学冶金工程学院,分子工程与应用化学研究所,安徽马鞍山243002

出　　处：《安徽工业大学学报（自然科学版）》2014年第2期152-156,217,共6页Journal of Anhui University of Technology（Natural Science）

基　　金：国家自然科学基金项目(50903001);安徽高校自然科学研究项目(KJ2013A063)

摘　　要：以1-氯-4（4-氯苯基）酞嗪为原料,用吩噻嗪上氮原子取代1号位的氯原子生成新化合物1-吩噻嗪-4（4-氯苯基）酞嗪（PzCBP）,采用核磁、质谱、单晶X射线衍射对其分子结构进行表征.选择14种主要的过渡金属及碱土金属阳离子对其进行荧光滴定实验,研究PzCBP对金属离子的荧光响应性质.结果表明：PzCBP在乙腈溶液中的紫外吸收波长为288 nm,最大发射波长为413 nm;该化合物具有对Cu2＋的选择性荧光淬灭性能,其与Cu2＋的物质的量比值为1.0,在0～10 μmol/L范围内对Cu2＋的响应曲线进行拟合,检测限达到0.09 μmol/L,能作为Cu2＋的荧光探针.While 1-chlorine-4（4-chlorobenzene） phthalazine compounds was used as raw material, a new compound 1--phenothiazine-4（4-chlorobenzene） phthalazine （PzCBP） was synthesized by substitution phenothiazine for chlorine atoms of phthalazine ring. The structure of this compound was characterized by the NMR, mass spectroscopies and Single-crystal X-ray Diffraction. 14 kinds of major transition metals and alkaline earth metal cations were used to conduct fluorescence titration experiment, which was used to study the fluorescence response properties of the metal ions. The new compound displayed an ultraviolet absorption at 288 nm and a strong emission band centered at 413 nm in an acetonitrile solution. The quenching performance of PzCBP was evaluated by fluorescence spectroscopy, revealing high sensitivity and selectivity response to Cu^2＋ with the molar ratio of PzCBP and Cu^2＋ is 1.0. A linear response for Cu^2＋ was obtained in the range of 0-10 μmol/L with low detection limit of 0.09 μmol/L. Therefore, the compound can be applied as a Cu^2＋ fluorescence probe.

关 键 词：1-氯-4(4-氯苯基)酞嗪 吩噻嗪 荧光滴定 铜(Ⅱ)离子探针 

分 类 号：O482.31[理学—固体物理]