冠脉支架术后患者导致ISR的相关因素分析  

Analysis on Related Etiology Factors of In-stent Restenosis

作　　者：李涛[1] 

机构地区：[1]兰州军区兰州总医院心血管内科,甘肃兰州730050

出　　处：《河北医学》2014年第7期1092-1095,共4页Hebei Medicine

基　　金：甘肃省科委科技计划课题;(编号:2011-ZD-11)

摘　　要：目的:对冠状动脉支架植入术(PCI)后行冠脉造影复查的患者进行回顾性分析,探讨导致支架内再狭窄(ISR)的相关因素。方法:收集2010年1月至2012年12月在我院接受PCI并进行冠脉造影随访的冠心病患者100例,将其分为ISR组及非ISR组,分析可能导致ISR的可能性因素。结果:通过对可能与ISR相关的因素进行多因素Logistic回归分析显示,ISR的危险因素有:2型糖尿病(OR=5.697,95%CI 2.627-12.357)、支架长度>20mm(OR=4.832,95%CI 2.385-9.667)、支架直径<3mm(OR=3.022,95%CI 1.899-4.809)、非药物涂层支架(OR=8.827,95%CI 2.758-28.249)以及多支病变(OR=9.095,95%CI 1.012-81.759)。结论:糖尿病、支架长度>20mm、支架直径<3mm、非药物涂层支架及多支血管病变是可以独立预测ISR发生的危险因素。Objective：To analyze the in-stent restenosis （ ISR） by recheck the coronary angiograms of the patients who accepted （ percutaneous coronary intervention ） PCI therapy , in order to find the possible risk factors of ISR .Method：100 （ coronary heart disease ） CHD patients who underwent （ coronary angiography） CAG after PCI therapy in our hospital from Jan .2010 to Dec.2012 were included in the study .They were divided into 2 groups：restenosis group and non-restenosis group .Then the two groups were compared to estimate the risk factors .Result： By the multiple logistic regression analysis , it was revealed that there were five significant risk factors for ISR：Diabetes mellitus （OR=5.697,95%CI 2.627-12.357）, the length of stent≥20mm （OR=4.832,95%CI 2.385-9.667）, the diameter of stent ≤3mm （OR=3.022,95%CI 1. 899-4.809）, non-drug-coated stents （OR=8.827,95%CI 2.758-28.249） and muti-vessel lesion （OR=9.095,95%CI 1.012-81.759）.Conclusion：The major reasons of in-stent restenosis are diabetes mullitus , the length of stent ≥20mm, the diameter of stent ≤3mm, non-drug-coated stents, muti-vessel lesion.

关 键 词：冠心病 冠脉介入术 支架内再狭窄 

分 类 号：R541.4[医药卫生—心血管疾病]