鲍曼不动杆菌肺炎41例临床及药敏分析  

Acinetobacter baumannii Pneumonia: A n Analysis of Clinical Features and Antibiotic Susceptibility of 52cases

作　　者：龚燕[1] 徐雯霞[1] 傅立华 

机构地区：[1]上海瑞金医院卢湾分院呼吸科,上海200020

出　　处：《北方药学》2014年第6期15-16,共2页Journal of North Pharmacy

摘　　要：目的：分析和总结鲍曼不动杆菌肺炎的临床特点和对抗生素敏感性的分布情况；方法：对41例鲍曼不动杆菌肺炎的临床资料进行统计分析，测定该菌的药物敏感性；结果：41例中，老年患者37例（90.24%），患有基础疾病患者41例（100%），其中，11例（26.83%）有慢性阻塞性肺病病史，25例（60.98%）存在低蛋白血症；院外感染14例（34.15%），院内感染27例（65.85%）。临床表现主要为咳嗽41例（100%），咳痰41例（100%），发热26例（63.41%），呼吸困难28例（68.29%）；胸部X线均呈现程度不等肺部浸润阴影。药敏检测表明，除了对阿米卡星、高剂量的庆大霉素、头孢吡肟、氨苄西林/舒巴坦比较敏感外（58.49%-41.94%），该菌广泛耐药。结论：鲍曼不动杆菌肺炎好发于老年、有基础疾病及免疫功能低下者，及早选择可能敏感的抗生素及进行细菌药敏检测将有益于改善预后。Objective：To analyze and summarize the clinical features and distribution of antibiotic susceptibility of Acinetobacter baumannii pneumonia .Methods：We statistically analyzed the clinical data of fifty-two cases of Acinetobacter baumannii and determined drug susceptibility of this bactiria .Results ：37 out of 41（that is 90.24%）cases were old age patients.100%patients were with underlying disease,while 11（26.83%）cases had chronic obstructive pulmonary disease history,25（60.98%） cases were with hypoproteinaemia .Out-of hospital infection and nosocomial infection were 14（34.15%）cases and 27（65.85%）,respectively. The cliniccal symptoms were mainly cough, expectoration（100%）,26（63.41%） cases had fever,28cases（68.29%）had dyspnea. Chest X-ray showed different-degree shadow on lungs.Besides Amikacin、Gentamicin with high dose、cefepime、ampicillin ／sulbactam were susceptive （58.49%-41.94%）,the drug susceptibility test showed.Conclusion ：The risk factors of Acinetobacter baumannii pneumonia were ageing,underlying diseases and immunodeficiency.Early choosing susceptive antibiotics and drug sensitivity test would improve the prognosis.

关 键 词：鲍曼不动杆菌 肺炎 药物敏感性 

分 类 号：R563.1[医药卫生—呼吸系统]