2951例病原菌的分布及其对常用抗菌药物的耐药分析  

Distribution and Antimicrobial Resistance Analysis for Commonly Used Antibiotics of 2951 Pathogens

作　　者：吕建华[1] 李改素[1] 李永兵[1] 

机构地区：[1]濮阳市人民医院,河南濮阳457000

出　　处：《中国药物警戒》2014年第6期366-368,共3页Chinese Journal of Pharmacovigilance

摘　　要：目的了解我院临床分离出的2951例病原菌对常用抗菌药物的耐药性。方法对2951株临床分离菌株进行药敏试验。结果临床分离菌株中革兰阳性菌占17.45%,革兰阴性菌占82.55%。革兰阳性球菌对万古霉素、利奈唑胺高度敏感;革兰阴性杆菌对头孢哌酮舒巴坦、哌拉西林他唑巴坦、亚胺培南和美罗培南敏感性较高。结论肠杆科大肠埃希菌耐药率高于肺炎克雷伯菌,非发酵菌的鲍曼不动杆菌、铜绿假单胞菌显示多重耐药。Objective To investigate the drug resistance of 2 951 pathogens for commonly used antibiotics. Methods Antimi-crobial susceptibility testing of 2 951 isolated bacteria was carried out. Results Of 2 951 clinical isolates gram-positivebacteria accounted for 17.45% and gram-negative bacteria accounted for 82.55%. Sensitivity of gram-positive cocci tovancomycin and linezolid was high; gram-negative bacilli showed higher sensitivity to cefoperazone sulbactam,piperaciUin-tazobactam, imipenem and meropenem. Conclusion The drug resistance rate of Escherichia coil washigher than Klebsiella pneumomae; Acinetobacter baumannii and Pseudomonas aeruginosa display multiple drugsresistance.

关 键 词：抗菌药物 病原菌 革兰阳性菌 革兰阴性菌 

分 类 号：R969.3[医药卫生—药理学] R37[医药卫生—药学]