Graves病孕妇血清促甲状腺受体抗体的检测价值  

The Detection Value Significance of Graves Disease Maternal Serum Thyrotropin Receptor Antibody

作　　者：卢洪文[1] 柳林[1] 张金环[2] 黄灵玉[1] 

机构地区：[1]潍坊市人民医院,山东潍坊261041 [2]潍坊市妇幼保健院,山东潍坊261011

出　　处：《中国医药指南》2014年第17期10-11,共2页Guide of China Medicine

摘　　要：目的分析检测患Graves病孕妇血清中促甲状腺激素受体抗体(TRAb)的临床价值。方法选择我院诊治的35例患Graves病孕妇作为实验组,另选35例健康体检孕妇作为对照组,ELISA法检测两组孕妇血清中TRAb浓度,化学发光免疫法检测游离三碘甲腺原氨酸(FT3)、游离甲状腺素(FT4)的含量水平。结果实验组孕妇血清中TRAb、FT3、FT4含量明显高于对照组,服用药物治疗3个月含量仍然高于正常值,6个月后趋于正常。结论检测孕妇Graves病患者血清中TRAb含量不仅对于Graves病的诊断、疗效观察有重要意义,还可指导临床治疗用药量及治疗时机。Objective Analysis testing of pregnant women suffering from Graves＆#39; disease serum thyrotropin receptor antibody（TRAb）clinical value. Methods 35 patients in our hospital for treatment of pregnant women suffering from Graves＆#39; disease as the experimental group, choose another 35 cases as a control group of healthy pregnant women, ELISA assay two maternal serum TRAb concentration, chemiluminescence immunoassay of free iodine Thyroid three original ammonia acid（FT3）, free thyroxine（FT4）levels levels.Results The maternal serum TRAb, FT3, FT4 levels signiifcantly higher, taking medication for 3 months is still higher than normal levels, after 6 months tended to be normal.Conclusion The maternal Graves TRAb levels in serum of patients with Graves＆#39; disease not only for diagnosis, efifcacy is important, but also to guide clinical treatment dosage and timing of treatment.

关 键 词：GRAVES病 促甲状腺激素受体抗体 孕妇血清 

分 类 号：R581.1[医药卫生—内分泌]