Management of mantle cell leukemia with cardiac involvement leading to cardiogenic shock  

作　　者：Muhammad Furqan Yamei Chen Akintunde Akinleye Judy Sarungbam Alan Gass Karen Seiter Delong Liu 

机构地区：[1]Division of Hematology and Oneology, Department of Medicine, Westchester Medical Center, 100 Woods Rd, Valhalla, NY 10595, USA [2]Department of Hematology, Xiamen Zhongshan Hospital, Xiamen University, Xiamen 361004, China [3]Department of Pathology, Westehester Medical Center, 100 Woods Rd, Valhalla, NY 10595, USA [4]Division of Cardiology, Department of Medicine, Westchester Medical Center, 100 Woods Rd, Valhalla, NY 10595, USA

出　　处：《Frontiers of Medicine》2014年第2期254-258,共5页医学前沿（英文版）

摘　　要：Mantle cell lymphoma is an aggressive subtype of B cell non-Hodgkin lymphoma. It can progress to leukemic phase but frank leukemic picture at initial presentation is not common. Leukemic phase indicates advance stage of the disease and generally associated with extensive extra-nodal involvement. Pericardial invasion has been reported, however we could not find a report of myocardial infiltration by this disease since the appraisal of the term ＂mantle cell lymphoma＂ in 1992. Here we report a case of cardiac involvement by mantle cell leukemia leading to cardiogenic shock which complicates the treatment decisions.Mantle cell lymphoma is an aggressive subtype of B cell non-Hodgkin lymphoma. It can progress to leukemic phase but frank leukemic picture at initial presentation is not common. Leukemic phase indicates advance stage of the disease and generally associated with extensive extra-nodal involvement. Pericardial invasion has been reported, however we could not find a report of myocardial infiltration by this disease since the appraisal of the term ＂mantle cell lymphoma＂ in 1992. Here we report a case of cardiac involvement by mantle cell leukemia leading to cardiogenic shock which complicates the treatment decisions.

关 键 词：mantle cell lymphoma BENDAMUSTINE cardiogenic shock 

分 类 号：S858.237.4[农业科学—临床兽医学] TP212.3[农业科学—兽医学]