高脂血症患者CAVI与其他心血管危险因素的关系  

Association between Cardio-ankle Vascular index and Atherosclerotic Risk Factors Among Patients with Hyperlipidemia

作　　者：吴多江[1,2] 余朝萍 杨静[1,2] 秦亚录[1,2] 曾洪燕[1,2] 晏明君 葛斌[1,2] 尹晓华[1,2] 刘天虎[1,2] 

机构地区：[1]郫县人民医院肾内科,四川成都611730 [2]郫县人民医院重症医学科,四川成都611730

出　　处：《四川医学》2014年第6期695-697,共3页Sichuan Medical Journal

基　　金：成都市科技协会基金项目(编号:2013539)

摘　　要：目的探索高脂血症患者心血管危险因素与心踝血管指数(cardio-ankle vascular index,CAVI)的相关性。方法选取体检人群高脂血症患者1360例,空腹测定脉压(pulse pressure,PP)、血脂、CAVI、踝臂指数(ankle-branchial index,ABI),以健康体检血脂正常1451例为对照组成2组,收集患者一般信息,包括年龄、性别、吸烟等数据,以单因素、多因素、以及logistic线性回归方法分别分析2组CAVI与性别、年龄、吸烟、PP、TG、TC、LDL-C、ABI的关系。结果 CAVI与性别无明显相关性,r值分别为:0.124,P均>0.05。两组分别作相关分析,结果和整体类似,但高脂血症组LDL相关系数r为0.039,P均>0.05;多元逐步回归分析显示,年龄、PP、TG、ABI对两组整体CAVI的影响是显著的,而TC、LDL-C对CAVI影响不显著。结论年龄、PP、TG、TC、ABI是CAVI的决定性因素,高脂血症患者尤其明显。Objective To study the association between cardio-ankle vascular index （ CAVI ） and conventional atherosclerotic risk factor in the Patients with hyperlipidemia. Methods 1360 cases of hyperlipidemia group and 1451 cases of non-hyperlipidemia control group according to LDL-C, serum biomarkers were measured in two groups, The association of CAVI with atherosclerotic risk factor was then analyzed. Results There were significantly difference in age, pulse pressure, low density lipoprotein cholesterin and ABI between two groups （P〈0. 05）. However, the CAVI values in patients with hyperlipidemia was higher than that of patients without hyperlipidemia with a statistically （P﹤0. 05）. Conclusion Age, PP, LDL-C, ABI are the decisive factors influencing on CAVI in patients with hyperlipemia.

关 键 词：心踝血管指数 高脂血症 危险因素 

分 类 号：R54[医药卫生—心血管疾病]