高血压患者心率减速力与室性心律失常  

The study on deceleration capacity of rate and its correlation with ventricular arrhythmia in patients with hypertensions

作　　者：张志敏 杜国峰 

机构地区：[1]上海市嘉定区南翔医院,201802

出　　处：《临床心电学杂志》2014年第2期91-93,共3页Journal of Clinical Electrocardiology

基　　金：上海市嘉定区卫生局基金项目(项目号:KYXM2010-12-02)

摘　　要：目的研究高血压患者的心率减速力,并分析其与室性心律失常的相关性。方法筛选无糖尿病和其他致自主神经功能损伤疾病的原发性高血压患者180例,以及同期健康体检者60例作为对照组,进行24h动态心电图检查,离线计算DC值、HRV时域指标,最后进行高血压与健康对照人群的对比分析,以及高血压患者的DC值和HRV时域指标与VA的相关性分析。结果高血压患者VA各组的DC值以及HRV时域指标的SDNN、SDANN、rMSSD、PNN50较对照组均显著降低(p<0.05),且高血压患者的DC、SDNN和SDANN与VA程度呈负相关(p<0.05)。结论高血压患者的DC值及HRV明显降低,且DC、SDNN、SDANN和PNN50与高血压患者VA程度呈负相关。早期对自主神经功能紊乱进行干预治疗,可能有利于减少高血压患者VA的发生。Objective To analyze deceleration capacity of rate and its correlation with ventricular arrhythmia in hypertension patients. Methods one hundred and eighty hypertension patients without diabetes and other autonomic nerve function injury disease were enrolled, sixty healthy check-up during the same period as control group.All participants 24 hours holter recording , the DC and time-domain HRV parameters was measured by the original definitions using digitized 24 hours Holter recording, the Comparative analysis of hypertension and healthy control group and The Correlation of DC and HRV with VA in patients with hypertension was analyzed finally. Results DC and SDNN,SDANN,pNN50,rMSSD in hypertension Group were notablely decreased than control group （p〈0.05） and there is negative correlation between DC, SDNN, SDANN and VA level （p〈0.05）. Conehmions The value of DC and HRV in patients with hypertension was significantly lower, and negatively correlated with VA levels in patients with hypertension. Early intervention on autonomic nervous function disorder may help to reduce the occurrence of VA in patients with hypertension.

关 键 词：高血压病 心率减速力 室性心律失常 

分 类 号：R541.7[医药卫生—心血管疾病] R540.41[医药卫生—内科学]