孕期复发性外阴阴道假丝酵母菌病与胎膜早破的相关性研究  

Correlation of recurrent vulvovaginal candidiasis and premature rupture of membranes during pregnancy

作　　者：向明[1] 蒋坤华[1] 张晓燕 何智妹 

机构地区：[1]广东省深圳市龙岗区人民医院,深圳518172 [2]广东省深圳市龙岗区坪地人民医院,深圳518117

出　　处：《右江医学》2014年第3期330-332,共3页Chinese Youjiang Medical Journal

摘　　要：目的探讨孕期复发性外阴阴道假丝酵母菌病(VVC)与胎膜早破的关联。方法选取43例复发性外阴阴道假丝酵母菌病的孕妇作为观察组,并与同期非复发性外阴阴道假丝酵母菌病的141例孕妇进行对比研究,随访两组孕妇的妊娠情况,比较胎膜早破与外阴阴道假丝酵母菌病发病次数的关系。结果观察组与对照组早产的发生率分别为18.6%VS 4.3%,胎膜早破发生率为34.9%VS 11.3%,两两比较差异均有统计学意义(P<0.05);而产褥感染及新生儿感染两组比较差异无统计学意义(P>0.05)。胎膜早破与1年内VVC发生次数的Spearman分析表明两者呈正相关性(r=0.216,P<0.001)。结论孕期复发性外阴阴道假丝酵母菌病可增加孕妇的早产、胎膜破裂,且胎膜早破的发生率与外阴阴道假丝酵母菌病发病次数呈正相关性。Objective To explore the correlation of recurrent vulvovaginal candidiasis（VVC） and premature rupture of membranes（PROM） during pregnancy.Methods 43 pregnant women with RVVC were selected as the observation group, and 141 pregnant women without recurrent vulvovaginal candidiasis as the control group.Then,all the pregnant women were followed up to observe their pregnancy and compare the relationship of PROM and frequency of VVC. Results The incidence of preterm delivery in the observation group and the control group was 18.6 % and 4.3 %,re- spectively and their incidence of PROM was 34.9% and 11.3 %, respectively.The differences of pairwise comparison were statistically significant （ P 〈0.05）. However, difference of puerperal infection and neonatal infection between groups was not statistically significant（ P 〉 0.05）. Spearman analysis showed that PROM and frequency of VVC within a year was positively correlated （ r=0.216, P 〈0.001）.Conclusion Recurrent vulvovaginal candidiasis of pregnant women may increase premature delivery and PROM. The incidence rate of PROM is positively correlated with frequency of VVC.

关 键 词：孕期 VVC RVVC 胎膜早破 

分 类 号：R714.25[医药卫生—妇产科学] R714.433[医药卫生—临床医学]