高效毛细管电泳在西北中藏药黄酮类化合物中的应用研究  

High Performance Capillary Electrophoresis in the Northwest Tibetan Medicine Flavonoids in the Applied Research

作　　者：高瑞斌[1] 杨艳[2] 董树清[3] 倪京满[2] 郭玫[1] 赵亮[3] 

机构地区：[1]甘肃中医学院药学系中(藏)药化学与质量研究省级重点实验室,甘肃兰州730000 [2]兰州大学药学院,甘肃兰州730000 [3]中国科学院兰州化学物理研究所西北特色植物资源化学重点实验室,甘肃兰州730000

出　　处：《亚太传统医药》2014年第12期5-8,8+7,共4页Asia-Pacific Traditional Medicine

基　　金：中科院科技支新项目(2011-2013);兰州市科技专项计划(2011-1-156)

摘　　要：西北中藏药作为中国特有的高原植物,长期生长于强辐射、日照时间长的环境下,具有有效成分含量高、生物活性强等优势。然而,目前对于该类药物的质量标准研究还十分有限,常用技术不能满足其质量和开发研究。因此采用新型分离分析技术,即高效毛细管电泳技术(HPCE),利用其高效、快速、进样体积小、多模式等特点,对西北中藏药中黄酮类化合物展开分析研究。综述不同分离模式下利用电泳技术对西北中藏药中黄酮类化合物及其它活性成分进行研究的文献报道,以期为其开发利用提供科学依据。As a native plateau plant to China, Chinese-Tibetan medicine in Northwest has the characteristics of strong radiation, long sunshine, higher accumulation of effective ingredients and higher bioaetivity. However, at present, the studies on the quality standard of such medicine are limited. Common techniques are no guarantee of the quality and research of Chinese-Tibetan medicine in Northwest. Therefore, we need to adopt a new-type technique for sample analysis and separation, i.e. high performance capillary electrophoresis （HPCE）, expanding analysis research for flavonoids of Chinese-Tibetan Medicine in Northwest with the help of the characteristics of high efficiency.high speed,sampling with small size and multimode. This paper reviews the reports in literatures a bout the research of the electrophoresis technique （HPCE）for flavonoids and other active ingredients of Chinese-Tibetan medicine in Northwest in different separation modes.

关 键 词：高效毛细管电泳 黄酮类化合物 西北中藏药 

分 类 号：R285[医药卫生—中药学]