流动注射化学发光法测定安痛定注射液中的氨基比林  

Flow Injection-Chemiluminescence Determination of Amidopyrine in the Antondin Injection

作　　者：何云华[1] 聂峰[1] 吕九如[2] 

机构地区：[1]汉中师范学院化学系,汉中723000 [2]陕西师范大学化学系,西安710062

出　　处：《分析化学》2001年第3期296-298,共3页Chinese Journal of Analytical Chemistry

摘　　要：在甲醛存在下 ,高锰酸钾与氨基比林能够发生化学发光反应 ,产生很强的化学发光 ,据此采用流动注射技术建立了一种测定氨基比林的化学发光分析法。方法的检出限为 3 .0× 10 -8g/mL ,相对标准偏差为 1.3 % (4 .0× 10 -6g/mL氨基比林 ,n =11) ,线性范围为 1.0× 10 -7～ 8.0× 10 -5g/mL氨基比林。该法已用于安痛定注射液中氨基比林含量的测定。The chemiluminescence reaction of amidopyrine-potassium permanganate with formaldehyde as an enhancer was investigated by now injection system. A method for the determination of amidopyrine on the basis of this technique was proposed. The detection limit is 3.0 x 10(-8) g/mL, the relative standard deviation is 1.3% (4.0 x 10(-6) g/mL amidopyrine, n = 11). The linear range is 1.0 x 10(-7) similar to 8.0 x 10(-5) g/mL amidopyrine. The method has been applied to the determination of amidopyrine in the antondin injection.

关 键 词：化学发光分析 高猛酸钾 氨基比林 流动注射 解热镇痛药 安痛定注射液 含量测定 

分 类 号：O657.3[理学—分析化学]