我国大陆地区各省不同类型病毒性肝炎报告发病率的系统聚类分析  

Hierarchical clustering analysis on the reported incidence of different types of viral hepatitis in China's Mainland

作　　者：刘尚辉[1] 娄岩[1] 邓妍[1] 刘壮[1] 关鹏[1] 郭海强[1] 

机构地区：[1]中国医科大学,辽宁沈阳110001

出　　处：《实用预防医学》2014年第6期641-644,共4页Practical Preventive Medicine

基　　金：国家自然科学基金(项目编号:71073175)

摘　　要：目的探讨我国大陆地区各省区2011年不同类型的病毒性肝炎发病情况的分布特点,为肝炎的预防控制提供参考。方法收集2011年我国31个省区各型肝炎的报告发病率,对其进行统计描述、线性相关分析和Q型系统聚类分析,Q型聚类分析的距离测量采用组间平均法。结果我国的肝炎发病以乙肝为主,各省间肝炎的总报告发病率、甲肝、乙肝、丙肝报告发病率之间存在正相关关系,聚类分析结果为肝炎合计报告发病率,甲型肝炎、乙型肝炎和丙型肝炎的报告发病率均位于各省区前列的甘肃、青海、新疆最早聚为一类,随后未分型肝炎报告发病率明显偏高的福建省也单独归为一类。结论我国肝炎高发区特征明显,肝炎总报告发病率、甲乙丙肝炎报告发病率均居全国前列,明显高于全国平均发病水平,应重点加强此类地区的肝炎防制工作。肝炎低发区发病特点不明显,更接近一般发病水平。Objective To explore the epidemic characteristics of different types of viral hepatitis in China's Mainland in 2011 so as to provide reference for preventing and controlling the diseases. Methods We collected the data about the reported inci- dence rates of different types of viral hepatitis in 31 provinces of China's Mainland. Statistical description, linear correlation analysis and Q hierarchical clustering analysis were conducted to analyze the data by using the statistical software SPSS 15.0. Clustering distance was calculated by using the group - average clustering method. Results Type B viral hepatitis was the most preva- lent hepatitis in China's Mainland. The reported total incidence rate of all types of hepatitis and the reported incidence rates of hep- atitis A, B and C were all positively correlated. The results of hierarchical clustering analysis showed that Gansu Province, Qing- hai Province and Xinjiang Uygur Autonomous Region with the highest reported total incidence rates of all types of viral hepatitis and the highest reported incidence rates of hepatitis A, B and C were classified into the same group firstly. Secondly, Fujian Province with the highest reported incidence rate of unclassified hepatitis was clustered into one group exclusively. Conclusions The reported total incidence rate of all types of viral hepatitis and the reported incidence rates of hepatitis A, B and C of the high- prevalence regions rank firstly across the country, which are all significantly higher than the national average levels, and hence, more attention should be paid to prevention and control of hepatitis in the these regions. The reported incidence rates of the low incidence regions are closer to the general reported incidence levels, and the epidemic characteristics are not obvious.

关 键 词：病毒性肝炎 系统聚类分析 地区分布 报告发病率 

分 类 号：R183.9[医药卫生—流行病学]