混合邻间对甲酚制备化工中间体的工艺研究  

Study on the Synthesis of Chemical Intermediate from the Mixture of o-Cresol, m-Cresol and p-Cresol

作　　者：吴鸿宾 

机构地区：[1]铜陵天泽化工有限公司,安徽铜陵244000

出　　处：《安徽化工》2014年第3期41-43,共3页Anhui Chemical Industry

摘　　要：以介孔分子筛为催化剂,催化烷基化混合邻间对甲酚制备6-叔丁基邻甲酚、6-叔丁基间甲酚、2-叔丁基对甲酚混合液,并精馏获得三种叔丁基甲酚纯品。考查了催化剂用量、异丁烯用量、反应温度等反应条件对烷基化反应的影响,确定了最佳工艺条件。结果表明,催化剂为三混甲酚用量的2.0%(质量),异丁烯用量与三混甲酚用量之比为1.05∶1(摩尔比),最佳反应温度为95℃的反应条件下,三混甲酚的总转化率达到96.25%以上,反应液中目标产品含量达94.67%,产品选择性可达98.36%。精馏后,6-叔丁基邻甲酚、6-叔丁基间甲酚、2-叔丁基对甲酚三种产品的质量含量分别为99.75%、99.57%、99.54%。整个工艺过程安全环保,成本低,能耗低,收益高。The alkylation reaction of mixture of o-cresol,m-cresol and p-cresol catalyzed by mesoporous molecular sieve catalyst to 2-tert-butyl-o-cresol,6-tert-butyl-m-cresol and 2-tert-butyl-p-cresol was studied. The effects of reaction conditions,namely catalyst dosage,isobutene dosage and reaction temperature were investigated. The reaction conditions were determined. The experimental results showed that the conversion could reach 96.25%, the selectivity could reach 98.36 % under the reaction conditions of reaction： catalyst/the cresol mixture weight ratio of 2%, temperature 95℃. The process is safe and environmentally friendly with low cost and low energy consumption.

关 键 词：6-叔丁基邻甲酚 6-叔丁基间甲酚 2-叔丁基对甲酚 混甲酚 异丁烯 介孔分子筛催化剂 

分 类 号：O625.311[理学—有机化学]