纤花线纹香茶菜的水溶性化学成分  

Water-soluble Chemical Constituents from Rabsodia lophanthoides

作　　者：匡艳辉[1] 林青[1,2] 梁斯[1] 姚小华[1] 王智民[2] 李楚源[1] 

机构地区：[1]广州白云山和记黄埔中药有限公司,广州510515 [2]中国中医科学院中药研究所,北京100700

出　　处：《中国实验方剂学杂志》2014年第13期110-112,共3页Chinese Journal of Experimental Traditional Medical Formulae

基　　金：中国博士后科学基金(20110490555);国家"重大新药创制"科技重大专项(2009ZX09301-005;2009ZX09308-003)

摘　　要：目的：研究纤花线纹香茶菜Rabsodia lophanthoides var.graciliflora的水溶性化学成分.方法：采用柱色谱分离技术进行分离纯化,运用MS和NMR分析鉴定化合物结构.结果：分得5个化合物,分别鉴定为咖啡酸（3,4-dihydroxycinnamic acid,1）、芹菜素-6,8-C-二-β-D-吡喃葡萄糖（apigenin-6,8-C-di-β-D-glucopyranoside,2）、异夏佛托苷（isoschaftoside,3）、夏佛托苷（schaftoside,4）和迷迭香酸（rosmarinic acid,5）.结论：其中化合物2～4为首次从该药用植物中分离鉴定.Objective： To clarify the water-soluble chemical constituents of Rabsodia lophanthoides var. graciliflora, one of the original plants of R. serra, a Chinese herbal medicine with protective effects on liver and gallbladder. Method： The aqueous extract of the whole plant was separated by various chromatographic methods and the compounds and their structures were identified by MS and NMR analyses. Result： Five compounds were isolated, their structures were identified as 3, 4-dihydroxycinnamic acid （1）, apigenin-6, 8-C-di-β-D- glucopyranoside （2） , isoschaftoside （3） , schaftoside （4） and rosmarinic acid （5） by spectroscopic data. Conclusion： Compounds 2-4 were isolated and identified from this plant for the first time.

关 键 词：纤花线纹香茶菜 溪黄草 黄酮 

分 类 号：R284.1[医药卫生—中药学]