孕激素受体在雌性山羊颈动脉体的分布  

Immunohistochemical Localization of PR in the Carotid Body of Female Goats

作　　者：李强[1] 金秀芳[1] 黄双[1] 徐永平[1] 孙曼[1] 郭晓[1] 陈文东[1] 董伟[1] 

机构地区：[1]西北农林科技大学动物医学院,陕西杨凌712100

出　　处：《西北农业学报》2014年第6期38-42,共5页Acta Agriculturae Boreali-occidentalis Sinica

基　　金：陕西省农业推广项目(k332021309);国家自然科学基金(31072184)

摘　　要：为了证实孕激素受体是否存在于雌性山羊颈动脉体。取雌性山羊的颈动脉体,经免疫组织化学SP法染色后,观察孕激素受体在颈动脉体的分布特点。结果表明,在雌性山羊的颈动脉体的Ⅰ型细胞、Ⅱ型细胞、血管内皮细胞均有不同程度的阳性染色。Ⅰ型细胞中PR强阳性产物分布于细胞膜,中等阳性产物分布于整个细胞质中;Ⅱ型细胞和血管内皮细胞有强阳性产物分布。证实孕激素受体在雌性山羊颈动脉体中分布广泛,提示颈动脉体可能接受孕激素的调节,这为研究孕激素非生殖调节功能及颈动脉体的神经内分泌调节机制提供了形态学依据。This experiment was to detect the existence of progesterone receptors（PR）in the carotid body（CB）of female goats.The carotid bodies were taken from mature female goats.The distribution characteristics of PR were observed after immunohistochemical SP staining.The results showed that：for typeⅠcells,strong PR immunoreactivity（PR-ir）and moderate PR-ir products distributed on the membrane and the whole cytoplasm,respectively;the typeⅡcells and Vascular endothelial cells were strong positive.The wide distribution of PR in CB implied that the progesterone may regulate CB,which provided morphologic basis for studies on non-reproductive regulating function of progesterone and neuroendocrine regulation of CB.

关 键 词：颈动脉体 孕激素受体 免疫组织化学SP法 山羊 

分 类 号：S827[农业科学—畜牧学]