1例制药企业职业性变应原致职业性哮喘死亡病例分析  

Analysis on a death case of occupational asthma caused by occupational allergen in a pharmaceutical factory

作　　者：黄燕[1] 张瑞丹[1] 杨丽莉[1] 高丽蕙 宋丽坤[1] 白净[1] 

机构地区：[1]石家庄市职业病防治院,河北石家庄050031

出　　处：《中国职业医学》2014年第3期295-296,共2页China Occupational Medicine

基　　金：河北省卫生厅资助项目(20120446)

摘　　要：目的对1例制药企业职业性变应原致职业性哮喘死亡病例进行分析。方法结合死者的职业史、现场职业卫生调查、死者就诊及抢救的病历资料,根据GBZ 57—2008《职业性哮喘诊断标准》进行诊断。结果死者既往无患病史,6年前调换工作岗位后出现典型的过敏性支气管哮喘临床表现及急性发作经过。工作中有乙二胺、6-氨基青霉烷酸结构的青霉素类、甲醛和过硫酸铵等多种职业性变应原接触史,在排除了其他可引起哮喘的原因后,最后被诊断为职业性重度哮喘。结论早发现、早诊断、早治疗、及早脱离致哮喘作业环境可有效避免职业性哮喘的发生,延缓病情发展,避免此类死亡事件的发生。Objective To analyze a death case of occupational asthma caused by occupational allergen in a pharmaceutical factory.Methods According to the occupational history , worksite survey of occupational health and history of the patient , the death case was diagnosed with GBZ 57—2008 Diagnostic Criteria of Occupational Asthma.Results The patient had no specific disease history , but six years ago after his changing of working position , he was showed the symptoms of typical allergic bronchial asthma .There were many kinds of occupational allergen exposure , such as ethanediamine , 6-aminopeni-cillanic acid-structured penicillin , formaldehyde and ammonium persulfate etc .After eliminating the other reasons causing asthma, occupational diagnostic group finally diagnosed the illness as heavy occupational asthma .Conclusion Occupa-tional asthma can be avoided by early physical examination , early medical diagnosis , early medical treatment and transfer to a better working environment .The process of the disease can be delayed , even avoided the occurrence of such deaths .

关 键 词：职业性 哮喘 变应原 职业健康检查 职业健康教育 

分 类 号：R135.1[医药卫生—劳动卫生]