发热性非溶血性输血反应的临床症状与防治  

The clinical symptom and the prevention of febrile non-hemolytic transfusion reaction

作　　者：项嘉亮[1] 黄伟刚[1] 赖金养[1] 

机构地区：[1]广东省江门市人民医院输血科,广东江门529000

出　　处：《中国当代医药》2014年第18期36-37,40,共3页China Modern Medicine

摘　　要：目的：探究发热性非溶血性输血反应（NHFTR）的临床症状表现及其防治方法。方法对本院于2010年6月~2011年12月接受输血治疗的287例患者的临床症状进行回顾性分析，观察与记录NHFTR的发生率，并行相关性分析。结果不同输血成分的NHFTR发生率比较，差异有统计学意义（P＜0.05）；共有27例患者发生NHFTR，其中11例为首次受血者，16例为多次受血者，供血者的白细胞、血小板等均与NHFTR的发生有显著相关性（P＜0.05）；多次受血者发生NHFTR的概率略高于首次受血者，但差异无统计学意义（P＞0.05）。结论 NHFTR的发生率较高，去除血液制品中的白细胞成分，能够有效抑制血液保存过程中细胞因子含量的增加，并有效预防NHFTR。Objective To explore the the clinical symptom manifestations and the prevention methods of non-hemolytic febrile transfusion reaction （NHFTR）. Methods The clinical symptom of 287 patients who accepted blood transfusion treatment in our hospital from June 2012 to December 2011 were retrospectively analyzed,the incidence rate of NHFTR was observed and recorded,and correlation analysis was done. Results There was a statistical difference of morbidity rate of different blood transfusion component （P〈0.05）;there were 27 cases of patients with NHFTR,among them,11 pa-tients were the first blood recipients,16 patients were blood recipients more than once,the white blood cell,platelet and so on of blood donors all had significant correlation with the occurrence of NHFTR （P〈0.05）;the occurrence probability of NHFTR in patients with multiple blood transfusion was a little higher than that of patients with the first blood trans-fusion,but there was no statistical difference （P〉0.05）. Conclusion The incidence rate of NHFTR is higher,removal of white cells in blood products can effectively inhibit the increase of blood cell factor in the preservation process,and ef-fectively prevent NHFTR.

关 键 词：发热性非溶性输血 发热反应 输血反应 白细胞因子 

分 类 号：R457.13[医药卫生—治疗学]