化妆品中双酚A的固相萃取-静态瞬稳化学发光测定法  

Determination of bisphenol A in cosmetics by static injection chemiluminescence combined with solid phase extraction

作　　者：孟磊[1] 鲁丽萍[2] 郑先福[1] 苏惠[1] 胡小宁 

机构地区：[1]河南农业大学理学院,河南郑州450002 [2]河南财政税务高等专科学校信息工程系 [3]河南农大迅捷测试技术公司

出　　处：《环境与健康杂志》2014年第4期344-345,共2页Journal of Environment and Health

基　　金：河南省教育厅科技研究重点项目(12A150012);郑州市科技攻关项目(083SGYG-24123-3)

摘　　要：目的建立化妆品中双酚A的静态注射化学发光测定法。方法根据碱性介质中双酚A对鲁米诺-高锰酸钾化学发光反应的抑制作用,以静态注射化学发光分析法测定化妆品中的双酚A。结果该方法的线性范围为1.0×10^-7～1.0×10^-3mol/L（r=0.993）,检出限为4.3×10^-3 mol/L,回收率为76.24%～94.21%,RSD为2.3%～4.2%（n=5）。结论该方法简单、快速、灵敏度高,适用于化妆品中双酚A的测定。Objective To develop a rapid and simple static injection chemiluminescence method to determine bisphenol A in cosmetics. Methods A mixture of luminol-potassium permanganate in the alkaline solution could create a stable chemiluminescence（CL） signal, and bisphenol A could inhibit the CL signal when it was poured into the mixture, based on it, then a method for the determination of bisphenol A with chemiluminescence by static injection of the luminal-potassium permanganate mixture was proposed. Results The linear range for the determination of bisphenol A was 1.0×10^-7-1.0×10^-3mol/L（r=0.993） with a detection limit of 4.3×10^-3mol/L. The rates of recovery were 76.24%-94.21%, the relative standard deviations were 2.3%-4.2%. Conclusion This method is simple, rapid, accurate and applicable to the determination of bisphenol A in cosmetics.

关 键 词：化学发光法 固相萃取 化妆品 双酚A 

分 类 号：O657[理学—分析化学]