超声心动图与右心导管对特发性肺动脉高压全肺阻力测量的相关性分析  

Correlation of Echocardiography and Right Heart Catheterization in Measure of Total Pulmonary Resistance in Idiopathic Pulmonary Arterial Hypertension

作　　者：王斌[1] 马小静[1] 张刚成[2] 何俊[1] 阳前华[1] 郑立娜[1] 严薇[1] 

机构地区：[1]武汉亚洲心脏病医院超声科,武汉430022 [2]武汉亚洲心脏病医院先天性心脏病中心,武汉430022

出　　处：《解放军医药杂志》2014年第6期22-25,共4页Medical & Pharmaceutical Journal of Chinese People’s Liberation Army

基　　金：国家十二五科技支撑项目(2011BAI11B15)

摘　　要：目的探讨超声心动图与右心导管测量特发性肺动脉高压(idiopathic pulmonary arterial hypertension,IPAH)全肺阻力(TPR)的相关性。方法对2013年1—12月在我院经右心导管检查确诊的IPAH 32例应用超声心动图诊断仪测量肺动脉瓣环心内膜面内径(DPV)、收缩期肺动脉瓣口前向血流速度(APV)和收缩期三尖瓣口右心房侧最大反流峰值速度(VmaxTR)并记录心率,根据测量结果计算肺动脉瓣环面积(APV)、肺动脉瓣流速-时间积分(VTIPV)和肺动脉平均压(PAMP),根据公式计算肺循环血流量(QP)和TPR,并与右心导管测量的结果进行对比。结果超声心动图诊断仪测量值经公式计算得出的PAMP、TPR、QP与右心导管测量结果均具有高度正相关(r=0.898、0.819、0.918,P<0.01)。结论应用超声心动图诊断仪测量TPR对临床无创诊断IPAH具有重要意义。Objective To explore the correlation of echocardiography and right heart catheterization in measure of total pulmonary resistance（ TPR） in idiopathic pulmonary arterial hypertension（ IPAH）. Methods A total of IPAH32 patients confirmed by right heart catheterization examination from January to December 2013 were recruited in the study. The values of pulmonary diagnostic endocardial surface of the inner diameter in the annulus（ Dpv）,systolic pulmonary blood flow before the valve orifice speed（ Vpv） and right atrial systolic tricuspid regurgitation of peak velocity max imum（ VmaxTR） were detected with ultrasoundcardiogram diagnostic apparatus,and the heart rates were recorded. The values of area of the pulmonary valve annulus（ APV）,the pulmonary valve flow velocity-time integral（ VTIPV） and mean pulmonary artery pressure（ PAMP） were calculated on the basis of the measure results,and values of pulmonary blood flow（ QP） and TPR were calculated according to the formula,and then the measure results of right heart catheterization were compared. Results Ultrasoundcardiogram diagnostic apparatus showed that values of PAMP,TPR and QP had a high positive correlation with the measure values of right heart catheterization by calculating with a formula（ r = 0. 898,0. 819,0. 918,P〈0. 01）. Conclusion Ultrasoundcardiogram diagnostic apparatus is of important significance in clinical noninvasive diagnosis of IPAH by TPR measure.

关 键 词：超声心动描记术 高血压 肺性 全肺阻力 

分 类 号：R544[医药卫生—心血管疾病]