成人非囊性纤维化性支气管扩张的诊治进展  

Progress of diagnosis and treatment on adult non-cystic fibrosis bronchiectasis

作　　者：席秀红[1] 毕晶[2] 李涛[1] 杨达伟[2] 卢水华[1] 王桂芳[2] 李倬哲[2] 白春学[2] 宋元林[2] 

机构地区：[1]上海市公共卫生临床中心,201508 [2]复旦大学附属中山医院呼吸科上海市呼吸病研究所,200032

出　　处：《国际呼吸杂志》2014年第12期953-957,共5页International Journal of Respiration

基　　金：国家自然基金（81170056）;上海市重点学科建设项目（B115）;上海市东方学者特聘教授基金

摘　　要：支气管扩张是慢性气道损伤引起支气管管壁肌肉和弹力支撑组织破坏所导致的一组支气管不可逆性扩张.其发病率在3.9/10万到52/10万左右,不发达国家发病率相对较高.在我国,支气管扩张被当做气道的一般化脓性炎症来治疗,但其病因、发病机制、针对性的治疗手段均研究甚少.文中结合目前的文献及2010年英国胸科学会的支气管扩张诊治指南,对非囊性纤维化性支气管扩张的诊治最新进展作简要述评。Bronchiectasis is a kind of irreversible bronchial dilation,which is caused by damage of bronchial wall muscle and elastic supporting tissue induced by chronic airway destruction.The worldwide incidence rate of bronchiectasis is 3.9/100 000 to 52/100 000,and the incidence rate in the developing country is relatively higher.In China,bronchiectasis is usually treated as purulent inflammation of the airway.However the studies on etiology,pathogenesis and targeted therapeutic method of bronchiectasis were limited.In this review,we studied current literature on bronchiectasis and combined with the diagnosis and treatment guideline for bronchiectasis from the British Thoracic Society in 2010 to briefly introduce the latest progress on the diagnosis and treatment of non-cystic fibrosis bronchiectasis.

关 键 词：支气管扩张 治疗 进展 

分 类 号：R562.22[医药卫生—呼吸系统]