1例室间隔缺损术后患儿的药学监护  

Pharmaceutical care on a child with postoperative complications of ventricular septal defect

作　　者：王延飞[1,2] 李泽[1] 史国兵[1] 赵庆春[1] 

机构地区：[1]沈阳军区总医院药剂科,辽宁沈阳110840 [2]沈阳药科大学药学院,辽宁沈阳110016

出　　处：《中国药物应用与监测》2014年第3期164-166,共3页Chinese Journal of Drug Application and Monitoring

摘　　要：1例11个月男性患儿,因感冒入院发现心脏杂音,超声心动图检查示:室间隔缺损,为行室间隔缺损修复术入院。患儿术后并发肺部感染,医生经验性给予头孢哌酮/舒巴坦,根据药敏结果且考虑患儿为幼龄,临床药师建议将本品替换为美罗培南;患儿术后继发肺动脉高压,建议在使用安立生坦、前列地尔的前提下,给予吸入用伊洛前列素;患儿术后并发室上性心动过速,给予艾司洛尔和胺碘酮抗心律失常,期间定期监测患儿血压、心率、血象及体温,并关注药物相关性不良反应。经对症治疗,患儿病情稳定出院。One 11-month-old male patient was admitted to hospital due to cold and heart murmur. The result of the ultrasonic cardiogram showed ventricular septal defect. The patient was admitted for repair of ventricular septal defect. After the operation, the patient was complicated by lung infection, secondary pulmonary hypertension and supraventricular tachycardia. Cefoperazone/sulbactam was empirically given to the patient for lung infection. Considering the results of drug sensitive test and age, clinical pharmacist suggested the antibiotic should be adjusted to meropenem. On the base of ambrisentan and alprostadil, it was suggested that the inhaled iloprost should be included in the treatment of secondary pulmonary hypertension. Esmolol and amiodarone were used for anti-arrhythmic therapy. The blood pressure, heart rate, hemogram and body temperature were regularly monitored, meanwhile the drug-related ADRs were also concerned about during the whole drug treatment by the clinical pharmacist. Finally the patient discharged with stable situation.

关 键 词：室间隔缺损 术后并发症 药学监护 临床药师 

分 类 号：R969[医药卫生—药理学]