高压氧治疗对急性减压病患者外周血肿瘤坏死因子α、白细胞介素-6的影响  

Effect of hyperbaric oxygenation on expression of tumor necrosis factor-α and interleukin-6 in decompression sickness

作　　者：司静琦[1] 闫磊[2] 雷晓芬[1] 

机构地区：[1]解放军第323医院,陕西西安710054 [2]解放军第273医院,新疆库尔勒841000

出　　处：《临床军医杂志》2014年第6期579-580,583,共3页Clinical Journal of Medical Officers

摘　　要：目的探讨高压氧治疗对急性减压病患者外周血肿瘤坏死因子α(TNF-α)和白细胞介素-6(IL-6)水平的影响。方法选取急性减压病患者30例,接受高压氧治疗,分别在治疗前,首次治疗结束即刻,治疗后第1、3、7天检测外周血TNF-α、IL-6水平。结果与治疗前比较,TNF-α水平在治疗后第1、3、7天明显下降;IL-6水平在治疗后第3、7天显著下降。结论高压氧治疗可以减少急性减压病患者外周血TNF-α、IL-6水平。Objective To study the effect of hyperbaric oxygenation （HBO） on the levels of tumor necrosis factor-α （TNF-α） and interleukin-6 （IL-6） in decompression sickness （DCS）. Methods The subjects included 30 patients with DCS, who were treated with HBO therapy. The levels of TNF-α and IL-6 were assayed before HBO therapy and 0 h and 1-, 3- and 7 day（s） after HBO therapy. Results The levels of TNF-α were significantly decreased 1-, 3- and 7 days after HBO therapy when compared with before. Moreover, the levels of IL-6 were also decreased 3- and 7 days after HBO therapy. Conclusion HBO makes the levels of TNF-α and IL-6 decrease significantly in the patients with DCS.

关 键 词：高压氧治疗 减压病 肿瘤坏死因子Α 白细胞介素-6 

分 类 号：R840.5[医药卫生—航空、航天与航海医学]