β-内酰胺类抗生素生产废液处理工艺研究  

Treatment of wastewater from β-lactam antibiotics

作　　者：周宝强[1] 刘冬[1] 曾嵘[1] 高瑞昶[1] 

机构地区：[1]天津大学化工学院,天津300072

出　　处：《现代化工》2014年第6期126-128,共3页Modern Chemical Industry

摘　　要：以应用于工业化生产为目的,得到了以化学合成和精馏分离的循环操作来处理β-内酰胺类抗生素生产废液的新工艺。直接从含有六甲基二硅醚的甲苯废液出发,以甲苯作为反应溶剂,体系中不引入新的组分直接合成目标产物N,N'-双三甲基硅脲,每个循环周期产物收率达到74.3%。讨论了不同精馏操作方式对纯甲苯收率的影响,使每个循环过程甲苯回收率达到80%以上。For the purpose of industrial production,the new cyclic process of chemical synthesis and distillation on treatment of wastewater from3-1actam antibiotics has been obtained.Using toluene wastewater containing hexamethyl disiloxane as raw material and toluene as solvent,the target product bis （trimethylsilyl）urea is directly synthesized without addition of any new substances.The yield of the product for each cycle reaches 74.3％.And the effects of different distillation operations on the yield of pure toluene are also studied.The optimized yield of toluene for each cycle is over 80％.

关 键 词：六甲基二硅醚 甲苯 N N'-双三甲基硅脲 催化剂 连续精馏 

分 类 号：TQ465[化学工程—制药化工]