人体腰椎L4～5节段有限元建模及分析  

Construction and Analysis of a Finite Element Model of Human L_(4-5) Lumbar Segment

作　　者：颜文涛[1] 赵改平[1] 方新果[1] 郭昊翔 马童[2] 凃意辉[2] 

机构地区：[1]上海理工大学医疗器械与食品学院,上海200093 [2]上海市杨浦区中心医院,上海200090

出　　处：《生物医学工程学杂志》2014年第3期612-618,共7页Journal of Biomedical Engineering

基　　金：国家自然科学基金资助项目(51106099);上海市教委科研创新资助项目(12YZ109)

摘　　要：本文基于CT图像数据结合图像处理软件建立人体腰椎L4～5节段有限元模型，进行前屈、后伸、侧弯和轴向旋转工况下的生物力学特性分析。首先，选择一名正常志愿者腰椎L4～5节段的CT图像数据建立三维模型，模型包括椎体、椎间盘、软骨终板、连接韧带和小关节突关节等部分，在前屈、后伸、侧弯和轴向旋转工况加载下进行生物力学性能的分析。结果表明，建立的腰椎模型几何形态逼真且验证有效，在500、1000、1500和2000N分布压力下，腰椎L4～5有限元模型的轴向位移分别为0．23、0．47、0．76、1．02mm，与前人在相同条件下离体实验和有限元分析的研究相近，几种情况下腰椎整体及椎间盘的应力分布符合腰椎的生物力学特性。因此，本文所建立的腰椎L4～5节段有限元模型能有效地模拟腰椎的生物力学特性，为后续腰椎植入物的生物力学性能研究奠定良好的基础。In the present study, a finite element model of L4-5 lumbar motion segment was established based on the CT images and a combination with image processing software, and the analysis of lumbar biomechanical characteristics was conducted on the proposed model according to different cases of flexion, extension, lateral bending and axial ro- tation. Firstly, the CT images of lumbar segment L4 to L5 from a healthy volunteer were selected for a three dimen- sional model establishment which was consisted of cortical bone, cancellous bone, posterior structure, annulus, nu- cleus pulposus, cartilage endplate, ligament and facet joint. The biomechanical analysis was then conducted accord- ing to different cases of flexion, extension, lateral bending and axial rotation. The results showed that the estab- lished finite element model of L4-5 lumbar segment was realistic and effective. The axial displacement of the proposed model was 0.23, 0.47, 0.76 and 1.02 mm, respectively under the pressure of 500, 1 000 , 1 500 and 2 000 N, which was similar to the previous studies in vitro experiments and finite element analysis of other people under the same condition. The stress distribution of the lumbar spine and intervertebral disc accorded with the biomeehanical properties of the lumbar spine under various conditions. The established finite element model has been proved to be effective in simulating the biomechanical properties of lumbar spine, and therefore laid a good foundation for the re search of the implants of biomechanical properties of lumbar spine.

关 键 词：腰椎L4~5节段 有限元建模 生物力学特性 

分 类 号：R318.01[医药卫生—生物医学工程]