抗苗勒管激素影响因素的研究进展  

Progress of Anti-Müllerian Hormone Influencing Factors

作　　者：张颖[1] 刘丽丽[1] 

机构地区：[1]辽宁医学院附属第一医院妇产科,锦州121000

出　　处：《生殖与避孕》2014年第6期492-496,共5页Reproduction and Contraception

基　　金：辽宁省自然科学基金(201102134);锦州市科学技术计划项目(12A1E35)

摘　　要：抗苗勒氏管激素(anti-Müllerian hormone,AMH)又称为苗勒管抵制物(Müllerian-inhibiting substance,MIS),是转化生长因子β(transforming growth factor,TGF-β)超家族的成员。AMH具有良好的稳定性,一般情况下在整个月经周期中无明显波动,但是仍有一些因素影响AMH的分泌水平,这些变化在临床中有着重要的意义和价值。本文从多囊卵巢综合征、年龄、肥胖、季节、卵巢储备和性分化异常等6个方面总结了可能引起AMH变化的因素,从而深入认识AMH变化的临床意义和价值。Anti-Miillerian hormone （AMH）, also known as Miillerian-inhibiting substance （MIS）, is a member of transforming growth factor-β （TGF-β） superfamily. Because of the stability of AMH, there is almostno significant fluctuation throughout the menstrual cycle. Several factors may influence the secretion of AMH, and these changes may imply significance clinical values, in order to better understand the clinical significancesand the value of AMH, this paper summarizes six factors that may affect AMH secretion, including PCOS, age, obesity, season, ovary reserve and abnormal sexual differentiation

关 键 词：抗苗勒管激素(AMH) 年龄 促卵泡生成素(FSH) 多囊卵巢综合征(PCOS) 肥胖 

分 类 号：R711.75[医药卫生—妇产科学]