中药抑糖方对链佐霉素糖尿病小鼠高血糖的影响  

Influence of Yitangfang, a traditional Chinese medicine, upon the high blood sugar of the experimental mice contracting streptozotocin diabetes

作　　者：胡莉娟[1] 王志洁[1] 朱生伟[2] 姚昌友[2] 郑向[1] 丁鹏 

机构地区：[1]湖北大学生命科学学院,湖北武汉430062 [2]湖北大学校医院,湖北武汉430062 [3]武汉市第三医院中医科,湖北武汉430060

出　　处：《湖北大学学报（自然科学版）》2001年第1期90-92,共3页Journal of Hubei University：Natural Science

摘　　要：用小剂量多次腹腔注射链佐霉素的方法 ,破坏胰岛 β细胞 ,诱发小鼠产生实验性胰岛素依赖型糖尿病 ,主要表现为血糖升高 .用一中药抑糖方剂灌喂小鼠 ,观察此方剂对链佐霉素糖尿病小鼠高血糖的影响 .结果提示 ,该方剂对链佐霉素引起的糖尿病有一定的预防保护作用 ,治疗作用尚未见明显效果 .The method of injecting small dosage of streptozotocin (STZ) to the experimental mice was adopted to disrupt their pancreas islet β cells and induce their experimental insulin-dependent diabetes which resulted in the high concentration of blood sugar. Yitangfang, a traditonal Chinese medicine, was administered to the suffering experimental mice, and the influence upon the high blood sugar of the suffering experimental mice was observed. The results indicated that Yitangfang took fairly good effect on prevention and protection against the streptozotocin diabetes although its tangible therapeutic effect was not observed yet.

关 键 词：链佐霉素 胰岛素依赖型糖尿病 中药 抑糖方 高血糖 小鼠 预防保护 治疗 

分 类 号：R259.871[医药卫生—中西医结合]