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机构地区:[1]河南中医学院,2011级研究生河南郑州450000 [2]河南中医学院第一附属医院,河南郑州450000
出 处:《中医临床研究》2014年第13期63-64,共2页Clinical Journal Of Chinese Medicine
摘 要:目的:观察心宝丸治疗慢性收缩性心力衰竭的临床疗效。方法:将120例心功能II、III级的慢性收缩性心力衰竭患者随机分为两组。两组均予西医常规治疗,治疗组60例加心宝丸,对照组加安慰剂丸剂,两组均治疗2个月。统计临床疗效,观察两组治疗前后心功能分级变化,检测左室射血分数(LVEF)正常率(LVEF>40%),进行血、尿、粪常规及肝、肾功能检查,观察药物不良反应。结果:两组心衰疗效比较,治疗组总有效率90.0%,对照组总有效率75.0%,两组总有效率比较差异有统计学意(P<0.05),两组中医症候疗效比较,有统计学意义(P<0.05),超声心动图比较无统计学意义。结论:心宝丸可明显改善慢性收缩性心力衰竭患者心功能,安全有效。Objective: To observe clinical effects of Xinbao Wan on chronic systolic heart failure. Methods: 120 patients were randomly divided into two groups. Bases on western conventional treatment, the treatment group was given Xinbao Wan, the control was given placebo. Before and after 2 months treatment, changes in cardiac function, left ventricular ejection fraction (LVEF) normal rate (LVEF〉40%), blood, urine, stool and liver and kidney function, adverse reactions were compared. Results: The total efficacy was 90.0% in treatment group, higher than 75.0% in the control; the difference was statistically significant (P〈0.05). TCM symptoms in two groups were compared with a statistical significance (P〈0.05), echocardiographs were compared with no statistical significance. Conclusion: Xinbao Wan is effectively safe, for improving cardiac function in patients with chronic systolic heart failure.
分 类 号:R541.6[医药卫生—心血管疾病]
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