中药银杏制剂的心血管药理效应:机制与展望  

Cardiovascular Pharmacological Effects of Traditional Chinese Medicine Ginkgo: Mechanisms and Prospects

作　　者：郭明[1,2] 刘玥[1,2] 许琳[3] 付长庚[1,2] 陈可冀[1,2] 

机构地区：[1]中国中医科学院西苑医院心血管病中心,北京100091 [2]中国中医科学院心血管病研究所,北京100091 [3]卫生部中日友好医院,北京100029

出　　处：《中国科学：生命科学》2014年第6期543-550,共8页Scientia Sinica(Vitae)

基　　金：北京市优秀博士学位论文指导教师科技项目(批准号:20138450201);北京市中医药科技发展资金资助项目(批准号:JJ2013-66);中国中医科学院西苑医院苗圃课题(批准号:XY13)资助

摘　　要：银杏是传统的活血化瘀中药,银杏制剂是现代科技开发的植物药中最为成功的案例之一.目前研究较多的银杏制剂是银杏酮酯,其主要活性成分为银杏黄酮、银杏内酯等,具有较为广泛的心血管药理效应,对多种心血管疾病具有较好的预防和治疗效果.本文对中药银杏制剂的主要活性成分、心血管药理效应及其机制、研究展望做一述评.Ginkgo is one of the traditional Chinese medicine （TCM） herbs for activating blood circulation and ginkgo preparation is one of the most successful cases of botanical drugs developed by modern science and technology. Ginkgo biloba extract, which mainly contains ginkgo flavonis and ginkgolides, is popular in the research field, has a wide range of cardiovascular pharmacological effects for prevention and treatment of a variety of cardiovascular diseases. In this paper, we review the main active ingredients, the cardiovascular pharmacological effects and their mechanisms of ginkgo preparations.

关 键 词：银杏 中药 心血管疾病 机制 展望 

分 类 号：R285[医药卫生—中药学]