超选择性前列腺动脉栓塞术治疗良性前列腺增生的初步应用  

Preliminary Application of Super-selective Prostatic Arterial Embolization in the Treatment of Benign Prostatic Hyperplasia

作　　者：袁凯[1] 王茂强[1] 段峰[1] 张国栋[1] 阎洁羽[1] 李凯[1] 

机构地区：[1]解放军总医院介入放射科,北京100853

出　　处：《中国医学影像学杂志》2014年第5期375-379,共5页Chinese Journal of Medical Imaging

基　　金：中央保健科研课题项目(2013BJ09)

摘　　要：目的评估超选择性前列腺动脉栓塞术治疗良性前列腺增生的安全性及有效性，为大样本临床应用提供依据。资料与方法3例良性前列腺增生患者均采用超选择性前列腺动脉栓塞术治疗，栓塞材料采用聚乙烯醇泡沫微球，直径90～180gm。栓塞前及栓塞术后1周、1个月、3个月复查，比较治疗前后患者的临床症状、前列腺体积的变化及术后并发症情况。结果3例栓塞技术均获得成功，其中病例1、病例2行双侧前列腺动脉栓塞；病例3由于右侧前列腺动脉开口重度狭窄使超选择性插管失败，行单侧前列腺动脉栓塞。术后随访3个月．2例行双侧前列腺动脉栓塞者临床症状明显改善，前列腺体积分别缩小51．09％、48．18％：仅行单侧前列腺动脉栓塞术者前列腺体积缩小28．45％，临床症状无明显改善。3例术后均未出现并发症。结论初步研宄结果表明，超选择性前列腺动脉栓塞术治疗良性前列腺增生安全、有效，而且双侧前列腺动脉栓塞短期疗效可能优于单侧。Purpose To evaluate the safety and efficacy of super-selective prostatic arterial embolisation （PAE） for the treatment of benign prostatic hyperplasia （BPH）, and to provide basis for large sample application. Materials and Methods Three patients with BPH underwent super-selective PAE treatment with Polyvinyl alcohol （PVA） foam particles （90-180 μm）. Clinical symptoms, prostatic volume （PV） and postoperative complications were used to assess the outcome before PAE and 1 week, 1 month, 3 months atter PAE. Results PAE was technically successful in all the 3 patients, among them patient 1 and patient 2 underwent bilateral PAE; patient 3 underwent unilateral PAE due to super-selective chatheterization failure caused by severe stenosis of the opening of right prostatic artery. Within 3 months＇ follow-up atter PAE, clinical symptoms improved significantly for the 2 patients who underwent bilateral PAE, with prostate volume decreased for 51.09% and 48.18% respectively; for the one patient who underwent unilateral PikE, prostate volume decreased for 28.45%, with no obvious clinical symptoms improvement. No postoperative complications were observed within all the 3 patients. Conclusion Preliminary application indicated that super-selective PAE is safe and effective for BPH, and bilateral PAE seems to lead to better short-term clinical results compared to unilateral PAE.

关 键 词：前列腺疾病 前列腺动脉栓塞术 介入放射学 

分 类 号：R697.32[医药卫生—泌尿科学]