子宫腺肌病发病机制及治疗研究进展  

Advance in study on the pathogenesis and treatment of adenomyosis

作　　者：蔡仕彬[1] 何佳[1] 

机构地区：[1]重庆医科大学生物医学工程学院,省部共建超声医学工程国家重点实验室培育基地,超声医学工程重庆市重点实验室,重庆400016

出　　处：《川北医学院学报》2014年第3期305-309,共5页Journal of North Sichuan Medical College

基　　金：国家重点基础研究发展计划(2011CB707900);创新能力建设项目(渝发改技【2013】384);2011年高等学校博士学科点专项科研基金联合资助课题(20115503110014);重庆市科技攻关项目([2007]11CSTC;2007AA5020)

摘　　要：子宫腺肌病是指子宫内膜腺体和间质侵入子宫肌层而引起的以月经过多、痛经为主要临床表现的子宫良性疾病。子宫腺肌病的发生发展机制十分复杂,血管生成、内膜细胞侵袭与增殖、甾体激素、免疫和遗传等相关因素均可能参与其中。子宫腺肌病的治疗困难,临床上根据患者的年龄、疾病严重程度及有无生育要求确定药物治疗或手术治疗(保守性或根治性手术)。Adenomyosis is a common benign uterine pathology that is defined by the presence of islands of ectopic endometrial tissue within the myometrium. There are some main clinical signs of menometrorrhagia and dysmenorrhea. It＇ s a complex process of occurrence and development of adenomyosis. It is connected to neoangiogenesis,invasion and proliferation of endometrium,hormonal abnormalities,lymphatic invasion and heredity. Because of the difficult treatment, there are several potential treatment options： medical （hormonal） or surgical treatment （conservative or radical）. A treatment will be chosen based on the patient＇ s symptomatology and whether she is interested in future child bearing.

关 键 词：子宫腺肌病 发病机制 促性腺激素释放激素激动剂 子宫切除术 高强度聚焦超声消融 

分 类 号：R711.74[医药卫生—妇产科学]