含吡啶的大环席夫碱锰(Ⅱ)配合物:合成、表征及抗菌性质(英文)  

Manganese(Ⅱ) Macrocyclic Schiff-Base Complexes Containing Pyridine Moiety:Synthesis and Characterization and Antibacterial Properties

作　　者：Keypour Hassan Liyaghati-Delshad Mozhdeh Rezaeivala Majid Khavasi Hamid Reza 

机构地区：[1]Faculty of Chemistry, Bu-Ali Sina University [2]Department of Chemical Engineering, Hamedan University of Technology [3]Department of Chemistry, Shahid Beheshti University, G.C., Evin

出　　处：《无机化学学报》2014年第7期1733-1740,共8页Chinese Journal of Inorganic Chemistry

基　　金：the Faculty of Chemistry of Bu-Ali Sina University and Ministry of Science, Research and Technology of Iran, for financial support

摘　　要：在Mn髤模板作用下,2,6-diacetylpyridine(DAP)及合适链状胺化合物通过[1+1]环缩合反应,合成了3个大环席夫碱配合物,并进行了红外、元素分析、质谱及电导率等表征及研究。测得了配合物[MnL1(CH3CN)](ClO4)2的晶体结构,中心离子呈现出稍微扭曲的五角锥配位构型。研究了配合物对S.aureus(ATCC 6633),B.cereus(ATCC 7064),C.xerosis(ATCC 373)(gram-positive bacterial strains),E.coli(PTCC 10009),K.pneuomoniae(MTCC 109),and P.vulgaris(lio)(gram-negative bacterial strains)的抗菌活性。结果显示[MnL3](ClO4)2抗菌活性明显优于[MnL1(CH3CN)](ClO4)2and[MnL2](ClO4)2。在25℃条件下0.1 mol·L-1 KCl溶液中,通过电位计量法测定了化合物的质子化常数。Three new macrocyclic Schiff-base complexes have been prepared via the Mn（Ⅱ） templated [1 ＋1] cyclocondensation of 2,6-diacetylpyridine （DAP） and appropriate linear amines. All complexes were characterized by IR spectra, elemental analysis, EI-Mass and conductivity measurements. The crystal structure of [MnL^1（CH3CN）] （ClO4）2 is also reported and exhibits a slightly distorted pentagonal-pyramidal geometry. Also the synthesized complexes were screened for their antibacterial activity against S. aureus （ATCC 6633）, B. cereus （ATCC 7064）, C. xerosis （ATCC 373） （gram-positive bacterial strains）, E. coli （PTCC 10009）, K. pneuomoniae （MTCC 109）, and P. vulgaris is greater have been （lio） （gram-negative bacterial strains）. The results show that the antibacterial activity of [MnL3]（ClO4）2 than that of [MnL^1（CH3CN）] （ClO4）2 and [MnL2] （ClO4）2. The protonation constants of three tetraamines determined potentiometrically in 0.1 mol·L^-1 KCl at 25℃.

关 键 词：大环配体 席夫碱 锰(Ⅱ)配合物 抗菌活性 质子化常数 

分 类 号：O614.711[理学—无机化学]