肝素抗凝血浆对钒酸盐氧化法测定总胆红素的影响  

INFLUENCE OF HEPARIN ON THE TOTAL BILIRUBIN LEVEL DETECTED BY VANADATE OXIDATION METHOD

作　　者：张伟雯[1] 杨凤啸[1] 

机构地区：[1]广州医科大学附属第三医院,广东广州510150

出　　处：《现代医院》2014年第6期73-74,77,共3页Modern Hospitals

基　　金：广东省中医药局建设中医药强省科研课题(编号:20131267)

摘　　要：目的探讨肝素抗凝血浆对钒酸盐氧化法测定总胆红素（Total Bilirubin，TB）结果的影响。方法采用钒酸盐氧化法平行测定300例患者的血清和肝素抗凝血浆标本中TB含量，并对两种方法的检测结果进行分析和比较。结果肝素抗凝血浆致钒酸盐氧化法测定TB结果降低。TB含量在1．7—300μmol／L范围内，肝素抗凝血浆的TB检测结果普遍低于血清2—45μmol／L；随着TB浓度的升高，检测结果的偏差越大；血清TB值y对于肝素抗凝血浆TB值X的校正公式为：y=1．1974x＋2．2047；线性试验和方法比较试验均显示两者具有良好的相关性。结论肝素抗凝血浆致钒酸盐氧化法测定TB结果降低。Objective To investigate the influence of heparin on the total bilirubin level detected by vanadate oxidation method. Methods Vanadate oxidation method was applied to detect total bilirubin in a range of 300 heparin anticoagulant plasma and serum samples. Results Heparin made low resalt in the detection of vanadate oxidation method ; the total bilirubin in beparin anticoagulant plasma was lower than serum. Conclusion In order to ensure the accurate and risible result; the serum samples should be adopted instead of heparin anticoagulant plasma samples.

关 键 词：肝素 钒酸盐氧化法 总胆红素 

分 类 号：R446.112[医药卫生—诊断学]