模拟氦氧480m饱和-493m巡回潜水研究  

Research on the simulated heliox 480 m saturation-493 m excursion dive

作　　者：肖卫兵[1] 张民[1] 方以群[1] 陈锐勇[1] 李慈[1] 冯磊[1] 马海鹰[1] 李富山 杨涛[1] 

机构地区：[1]海军医学研究所,上海200433 [2]海司航保部

出　　处：《中华航海医学与高气压医学杂志》2014年第2期73-75,97,共4页Chinese Journal of Nautical Medicine and Hyperbaric Medicine

基　　金：全军后勤“十一五”计划重大项目（AHJ06J006）.志谢 闫硕、姚健、黄志强、于峰涛、陈海庭、侯公林、何佳、顾靖华、巴剑波、袁恒荣、马骏、余浩、刘民航、陈双红等人员为本研究项目作出了贡献,在此表示衷心的感谢

摘　　要：目的 获取人体在高压耐受极限区域的潜水实验数据,完善相关医学保障措施.方法 由9名海军潜水员参与饱和深度65 ～480 m的系列氦氧模拟饱和潜水,采用改进的潜水程序、强化的医学监护措施和针对性的医学干预完善医学保障措施,并进行潜水员能力评价.结果 首次成功应用了建立在气泡学说基础上的我国饱和减压方案,证实了代谢组学在高气压环境下全面、无创性医学监护的优势,成功运用药物干预减轻了损伤性负荷,建立了压力敏感型人员的有效鉴别手段.结论 该研究取得的成果将丰富和深化高气压生理学内涵,为大深度潜水实践提供有效指导.Objective To acquire related data of a deep saturation dive which approaches the depth limit in terms of physiology,and to further improve medical service for such dives.Methods A series of simulated heliox saturation dives （saturation depths,65-480 m） were conducted by 9 naval divers.During the experiments,modified diving procedures,intensified medical surveillance measures,targeted medical intervention and performance evaluation were applied to ensure the success of the dive.Results Following research results were obtained：the decompression profile based on the bubble theory was developed and applied in a series of diving experiments ; the superiority of urine metabonomics in full-scale and noninvasive medical detection of divers at high pressure was demonstrated; pharmacological intervention was used to alleviate harmful loads; and effective identification means were established to distinguish pressure susceptible people.Conclusions The research results obtained from this project would enrich and deepen intimate knowledge on hyperbaric physiology and would be a good guidance for better medical supports in deep saturation dives.

关 键 词：饱和潜水 饱和减压 高压神经综合征 氧化损伤 代谢组学 压力敏感型人员 

分 类 号：R84[医药卫生—航空、航天与航海医学]