Transcriptional Repression by Histone Deacetylases in Plants  

作　　者：Xuncheng Liua Songguang Yang Minglei Zhaoa Ming Luo Chun-Wei Yu Chia-Yang Chen Ready Tai Keqiang Wu 

机构地区：[1]Key Laboratory of Plant Resources Conservation and Sustainable Utilization, South China Botanical Garden, Chinese Academy ofSciences, Guangzhou 510650, China [2]Institute of Plant Biology, National Taiwan University, Taipei [3]University of Chinese Academy of Sciences, Beijing 100049, China

出　　处：《Molecular Plant》2014年第5期764-772,共9页分子植物（英文版）

摘　　要：Reversible histone acetylation and deacetylation at the N-terminus of histone tails play crucial roles in regulation of eukaryotic gene activity. Acetylation of core histones usually induces an ＇open＇ chromatin structure and is associated with gene activation, whereas deacetylation of histone is often correlated with ＇closed＇ chromatin and gene repression. Histone deacetylation is catalyzed by histone deacetylases （HDACs）. A growing number of studies have demonstrated the importance of histone deacetylation/acetylation on genome stability, transcriptional regulation, and development in plants. Furthermore, HDACs were shown to interact with various chromatin remolding factors and transcription factors involved in transcriptional repression in multiple developmental processes. In this review, we summarized recent findings on the transcriptional repression mediated by HDACs in plants.Reversible histone acetylation and deacetylation at the N-terminus of histone tails play crucial roles in regulation of eukaryotic gene activity. Acetylation of core histones usually induces an ＇open＇ chromatin structure and is associated with gene activation, whereas deacetylation of histone is often correlated with ＇closed＇ chromatin and gene repression. Histone deacetylation is catalyzed by histone deacetylases （HDACs）. A growing number of studies have demonstrated the importance of histone deacetylation/acetylation on genome stability, transcriptional regulation, and development in plants. Furthermore, HDACs were shown to interact with various chromatin remolding factors and transcription factors involved in transcriptional repression in multiple developmental processes. In this review, we summarized recent findings on the transcriptional repression mediated by HDACs in plants.

关 键 词：histone deacetylases transcriptional repression plant development abiotic and biotic stresses. 

分 类 号：Q786[生物学—分子生物学] Q75