沙美特罗替卡松粉吸入剂联合清肺消炎丸治疗支气管哮喘急性发作的疗效观察  

Clinical observation of Salmeterol and Fluticasone Propionate Powder for Inhalation combined with Qingfei Xiaoyan Pills in treatment of acute attack of bronchial asthma

作　　者：肖凡[1] 李楠[1] 康桂艳[1] 韩力[1] 白显利[1] 王静[1] 姚丽花[1] 曹金钟[1] 

机构地区：[1]天津市第三医院呼吸科,天津300250

出　　处：《现代药物与临床》2014年第6期631-634,共4页Drugs & Clinic

摘　　要：目的观察沙美特罗替卡松粉吸入剂联合清肺消炎丸治疗支气管哮喘急性发作的临床疗效。方法选取2012年6月—2013年6月天津市第三医院收治的60例哮喘急性发作期轻、中度患者,分为对照组和治疗组,每组各30例。两组患者均按需使用速效β受体激动剂万托林。对照组给予沙美特罗替卡松粉吸入剂,1吸/次,2次/d。治疗组在对照组的基础上给予清肺消炎丸,8 g/次,3次/d。两组疗程均为14 d。观察两组患者治疗前后的临床疗效,肺通气功能及症状、体征的持续时间。结果治疗后,治疗组有效率明显高于对照组,差异具有统计学意义(P<0.05);两组患者治疗后肺通气功能均优于治疗前,且治疗组比对照组肺通气功能改善更明显,差异具有统计学意义(P<0.05);治疗组的胸闷、气短消失时间,咳嗽缓解时间及哮鸣音消失时间明显短于对照组,两组比较差异有统计学意义(P<0.05)。结论沙美特罗替卡松粉吸入剂联合清肺消炎丸治疗支气管哮喘急性发作疗效显著,值得临床推广。Objective To observe the clinical efficacy of Salmeterol and Fluticasone Propionate Powder for Inhalation combined with Qingfei Xiaoyan Pills in the treatment of acute attack of bronchial asthma. Methods Patients （60 cases） with acute attack of bronchial asthma in Tianjin Third Hospital from June 2012 to June 2013 were randomly divided into treatment and control groups （30 cases in each group）. The patients in the two groups were given short-acting β-agonists Ventolin according to the need. The patients in the control group were given Salmeterol and Fluticasone Propionate Powder for Inhalation, one sucktion once, two times daily. The patients in the treatment group were given Qingfei Xiaoyan Pills on the basis of the control group, 8 g once, three times daily. The patients in the both groups were treated for 14 d. The clinical efficacy, pulmonary function, and the duration of symptoms and signs were compared for the patients between the two groups. Results After the treatment, the effective rates in the treatment group were higher than those in the control group with significant difference （P 〈 0.05）. The pulmonary function of the patients after the treatment was significantly improved. The lung function index was significantly higher than that of the patients in the control group, and there was a significant difference between the two groups （P 〈 0.05）. The disappear time of chest tightness, the ease time of cough, and the disappear time of wheezing sound were shorter than those of the patients in the control group with significant difference （P 〈 0.05）. Conclusion Salmeterol and Fluticasone Propionate Powder for Inhalation combined with Qingfei Xiaoyan Pills has the remarkable clinical efficacy in the treatment of acute attack of bronchial asthma. It is worthy of clinical application.

关 键 词：沙美特罗替卡松粉吸入剂 清肺消炎丸 支气管哮喘急性发作 

分 类 号：R974[医药卫生—药品]