便携式表面等离子体共振生物传感器在低浓度溶液定量检测中的应用  被引量:8

Application of Portable Surface Plasmon Resonance Biosensor in the Quantitative Detection of Low Concentration Solution

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作  者:齐攀[1,2] 马骁[2] 钟金钢[2,3] 李莹[3] 

机构地区:[1]广东交通职业技术学院电子工程系,广东广州510650 [2]暨南大学光电工程系,广东广州510632 [3]暨南大学光电信息与传感技术广东普通高校重点实验室,广东广州510632

出  处:《激光与光电子学进展》2014年第7期157-163,共7页Laser & Optoelectronics Progress

基  金:国家自然科学基金(41206081);海洋赤潮灾害立体监测技术与应用国家海洋局重点实验室项目(MATHAB20120208);粵港关键领域重点突破招标项目(2005A20501001)

摘  要:针对现有低浓度溶液定量检测技术复杂、分辨率低等问题,将自行研制的角度扫描型便携式表面等离子体共振生物传感器应用于低浓度溶液定量检测。通过实验证明了该装置和方法在低浓度溶液定量检测中的可行性。对葡萄糖溶液和甘氨酸溶液做了定量检测实验,实验结果显示,直接检测葡萄糖溶液可分辨到0.1 mg/ml。基于表面等离子体共振的低浓度溶液定量检测方法操作简便,仪器便携,可实现快速、实时高分辨率检测。The self-developed portable angle scanning surface plasmon resonance biosensor is used in the quantitative detection of low concentration solution, because the existing quantitative detection methods are complicated and with low resolution. The validity of this method and the developed device is demonstrated by experiments. The quantitative detection is proceeded in glucose and glycine solutions. The detection results show that the direct detection of glucose solution distinguish the concentration of 0.1 mg/ml. The quantitative detection method of low concentration solution based on the surface plasmon resonance is simple. The developed device is portable and easy to operate. The rapid and real-time detection with high resolution can be realized by this method.

关 键 词:表面等离子体共振 便携式 生物传感器 定量检测 

分 类 号:TN247[电子电信—物理电子学]

 

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