一种糖基二苯甲酮类聚合物紫外线吸收剂的合成与性能  

Synthesis and Properties of Saccharide-Based Polymeric Ultraviolet Absorber Containing Benzophenone Groups

作　　者：高鹏飞[1] 汤艳峰[2] 朱金丽[2] 刘志勇[1] 

机构地区：[1]石河子大学化学化工学院新疆兵团化工绿色过程重点实验室,新疆石河子832003 [2]南通大学化学化工学院,江苏南通226019

出　　处：《精细化工》2014年第7期829-833,共5页Fine Chemicals

基　　金：国家自然科学基金(21376124)~~

摘　　要：以2,4-二羟基二苯甲酮（UV-0）为原料，与丙烯酰氯反应得到2-羟基-4-丙烯酸酯基-二苯甲酮（HAB），然后与糖单体3-O-丙烯酰基-1,2,5,6-O-双异丙叉-α-D-葡萄糖（OAIG）聚合，制备了poly（HAB-OAIG）（PHIG），最后PHIG经三氟乙酸水解得到了poly（HAB-co-3-O-烯丙基酰氯-α-D-葡萄糖）（PHG），采用IR、1HNMR和GPC对其进行了表征。并研究了聚合物的紫外吸收能力和抗光氧化能力，结果表明，PHG在280-360 nm内有良好的紫外线吸收效果，最大吸收波长为331 nm；MTT实验显示，不同浓度PHG浸提液处理的L929细胞相对细胞增殖率均大于80%，且随着浓度增大，相对细胞增殖率无明显降低，说明PHG具有良好的生物相容性。2-Hydroxy-4-acryloy benzophenone（HAB） was synthesized from acrylicchloride and 2,4-dihydroxybenzophenone（UV-0）. Poly（HAB-OAIG）（PHIG） was prepared by polymerization of HAB with 3-O-acryloyl-1,2,5,6-di-O-isopropynylene-α-D-glucose（OAIG）. Then, the copolymer poly（HAB-co-3-O-acryloyl-α-D-glucose）（PHG） was obtained by hydrolysis of PHIG via trifluoroacetic acid. These structures were characterized mainly by FTIR, 1HNMR and GPC. The UV-Vis spectroscopies revealed that PHG is of good ultraviolet absorption ability in the wavelength range of 280-360 nm, and the maximum absorption wavelength is 331 nm. MTT experiments showed the relative cell proliferation rate of L929 cells which were treated with different concentrations extracts of PHG is greater than 80%. And with the concentration increases, the relative appreciation rate was not significantly reduced. These data demonstrated that PHG has good biocompatibility.

关 键 词：高分子紫外线吸收剂 抗光氧化 2 4-二羟基二苯甲酮 生物相容性 功能材料 

分 类 号：TQ314.257[化学工程—高聚物工业]