同一周期单双次授精对供精人工授精妊娠率的影响  

Effect of performing one and two inseminations per cycle on pregnancy rate in artificial insemination by donor

作　　者：李静[1] 王兴玲[1] 杨晓娜[1] 李真[1] 于晓娜[1] 乔洪武[1] 张文[1] 

机构地区：[1]郑州大学第三附属医院生殖医学中心,河南郑州450052

出　　处：《中国妇幼健康研究》2014年第3期484-486,共3页Chinese Journal of Woman and Child Health Research

摘　　要：目的研究同一周期单次授精和双次授精对供精人工授精妊娠率的影响。方法收集2012年8月至2013年7月在郑州大学第三附属医院生殖医学中心进行的供精人工授精(AID)共568人次864个周期。回顾性分析同一周期单次授精、双次授精及首次注入不同精子数对供精人工授精妊娠率的影响。结果在568人次864个供精人工授精周期中,单次授精、双次授精妊娠率分别为29.77%和36.29%,双次授精妊娠率高于单次授精,差异具有统计学意义(x～2=3.438,P<0.05)。首次注入精子数≥1 000万条和<1 000万条的两组患者,前者单双次授精妊娠率分别为19.80%和34.93%,后者单双次授精妊娠率分别为10.00%和31.95%,双次授精妊娠率高于单次授精,差异具有统计学意义(首次注入精子数≥1 000万条:x～2=8.863,P<0.05;首次注入精子数<1 000万条:x～2=9.759,P<0.05)。结论围排卵期首次注入精子数≥1 000万条或<1 000万条,同一周期行双次人工授精可提高妊娠率。Objective To study the effect of performing one and two inseminations per cycle on pregnancy rate in artificial insemination by donor （ AID） .Methods Pregnancy rate was retrospectively analyzed when performing two inseminations per cycle in AID compared with one insemination per cycle among a total of 568 patients undergoing 864 cycles of AID at Reproductive Medical Centre of the Third Affiliated Hospital of Zhengzhou University during the period of August 2012 and July 2013.Results Pregnancy rate of performing two inseminations per cycle （36.29%） was significantly higher than that of one insemination per cycle （29.77%） in 864 cycles of AID （χ^2 =3.438, P 〈0.05）.Pregnancy rates of performing one insemination and two inseminations per cycle were 19.80% and 34.93% for patients with inseminated motile sperm≥10×10^6 , and they were 10.00% and 31.95% for those with inseminated motile sperm 〈10 ×10^6.The pregnancy rate of two insemination was significantly higher than that of one insemination （inseminated motile sperm≥10 ×10^6χ^2 =8.863,P 〈0.05; inseminated motile sperm 〈10 ×10^6： χ^2 =9.759, P 〈0.05）.Conclusion Two inseminations per cycle can enhance the pregnancy rate either inseminated motile sperm≥10×10^6 or inseminated motile sperm 〈10 ×10^6 around ovulation .

关 键 词：单次授精 双次授精 供精人工授精 妊娠率 

分 类 号：R715[医药卫生—妇产科学]