农民食管癌与心理 社会应激因素的1:2配对病例对照研究  

The 1:2 matched case-control study on psychosocial stress status of esophageal cancer in rural residents

作　　者：翟敏[1] 郭立燕[1] 赵霞[2] 张妍[1] 贺魁[1] 刘铁柱[1] 

机构地区：[1]济宁医学院公共卫生学院,山东济宁272067 [2]济宁医学院附属济宁市第一人民医院,济宁272011

出　　处：《济宁医学院学报》2014年第3期187-189,192,共4页Journal of Jining Medical University

基　　金：山东省医药卫生科技发展计划项目(编号:2011HZ015);济宁医学院科研计划重点项目(编号:JY2013KJ001)

摘　　要：目的探讨心理、社会应激因素与原发性食管癌发病的关系。方法按照1∶2匹配的病例对照研究,采用心理社会应激量表(PSSG)分别对152例病例组和304例对照组研究对象进行面对面测评,运用EpiData软件进行数据录入、整理,采用条件logistic回归分析方法对数据进行分析。结果病例组和对照组"生活事件L"、"消极应对NC"、"积极情绪体验PE"、"积极应对PC"及TS的得分均具有统计学差异(P<0.05),多因素条件logistic回归分析表明,家庭不和或婚姻问题、家人病重、个人健康变化等负性生活事件、"情绪压心底不表现又忘不掉"等消极应对方式,积极应对方式中的"能够尽快将不愉快忘掉,主动求助于别人、诉说"进入模型。结论负性生活事件、消极应对方式是食管癌发病的危险因素,积极应对方式为食管癌发病的保护因素。Objective To explore the relationship among psychosocial stress factors and primary esophageal cancer of farmers. Methods The 1 ： 2 matched case-control study was used,and psychosocial stress scale was con- ducted in 152 esophageal cancer cases and 304 controls.Results There were statistical difference of case and con- trol group among the L value of life events, the PE value of positive emotional experience, the PC value of positive response,and TS （P〈0.05）. Conclusion Multi-factor Logistic regression analysis showed significantly different in case group and control group of life events and coping styles. Conclusion Negative life events and negative coping style are risk factors of esophageal cancer, and positive approach are protective factors.

关 键 词：农民 食管癌 心理社会应激因素 

分 类 号：R1[医药卫生—公共卫生与预防医学]