盐酸恩诺沙星对蛋白核小球藻(Chlorella pyrenoidosa)的致毒效应研究  

Toxic Effect of Enrofloxacin Hydrochloride on Chlorella pyrenoidosa

作　　者：肖辉[1] 苏振霞[2] 边倩[2] 

机构地区：[1]江苏省海洋资源开发研究院,江苏连云港222005 [2]淮海工学院海洋学院,江苏连云港222005

出　　处：《淮海工学院学报（自然科学版）》2014年第2期85-88,共4页Journal of Huaihai Institute of Technology:Natural Sciences Edition

基　　金：江苏省海洋资源开发研究院开放课题(JSIMR201314);连云港市科技计划项目(CXY1220);江苏省高校优势学科建设工程资助项目

摘　　要：为探讨水产养殖中氟喹诺酮类药物残留对水生生物的毒性效应,研究了盐酸恩诺沙星对蛋白核小球藻(Chlorella pyrenoidosa)的急性毒性。结果显示,各药物质量浓度组对蛋白核小球藻的生长均有抑制作用,并且随药物处理质量浓度的增大,藻细胞的生长逐渐降低,显示出明显的剂量—效应关系。盐酸恩诺沙星对蛋白核小球藻的24,48,72,96h的EC50值分别为184.83,341.07,457.84,171.38μg/mL,叶绿素a和b的含量随着盐酸恩诺沙星处理质量浓度的增大呈现相同的变化趋势。In order to study the toxic effect of ftuoroquinolones on fresh algae,Chlorella pyrenoidosa was exposed to Enrofloxacin hydrochloride of five concentrations （15.625,31.25,50, 62.5 and 125μg/mL）.Results showed that Enrofloxacin hydrochloride had inhibition effect on the growth of Chlorella pyrenoidosa.With the increase of concentration,the inhibition increased correspondingly.The 24,48,72 and 96 h EC50 values of Enrofloxacin hydrochloride were 184.83, 341.07,457.84 and 171.38μg/mL respectively.Enrofloxacin hydrochloride had the same effect on the contents of chlorophyll-a and chlorophyll-b.

关 键 词：盐酸恩诺沙星 蛋白核小球藻 致毒效应 光合色素 

分 类 号：S948[农业科学—水产养殖]