晚期血吸虫病患者抑郁状况及其影响因素  

Analysis on depression of patients with advanced schistosomiasis and its influencing factors

作　　者：周瑞红[1] 潘洁[1] 肖水源[2] 罗志红[3] 刘科峰[1] 邵志伟[1] 余慧琼[1] 来如意[1] 袁钢[1] 

机构地区：[1]湖南省血吸虫病防治所附属湘岳医院、国家血吸虫病临床重点专科,岳阳414000 [2]中南大学公共卫生学院 [3]湖南省血吸虫病防治所

出　　处：《中国血吸虫病防治杂志》2014年第3期270-273,283,共5页Chinese Journal of Schistosomiasis Control

基　　金：湖南省科学技术厅科研项目(2011SK3190);国家临床重点专科建设项目

摘　　要：目的探讨晚期血吸虫病(晚血)患者抑郁状况及其影响因素。方法采用描述性研究设计,应用自编的一般资料调查表、抑郁自评量表、世界卫生组织生存质量测定量表简表对206例患者进行调查。结果 206例晚血患者抑郁发生率为69.4%,抑郁与生活质量各维度呈负相关(P=0.000);多因素Logistic回归分析显示住院次数(β=0.442,P=0.007)是晚血患者出现抑郁情绪的危险因素,而文化程度高(β=-0.583,P=0.011)、门静脉高压症手术史(β=-0.917,P=0.000)是患者出现抑郁情绪的保护因素。结论晚血患者抑郁发生率较高,受多方面因素的影响;应采取针对性干预措施以改善晚血患者的心理状况,降低其抑郁情绪的发生。Objective To explore the status of depression in patients with advanced schistosomiasis and its influencing fac-tors,so as to provide the evidence for improving psychological interventions. Methods A total of 206 patients with advanced schistosomiasis were investigated with the self-designed general information questionnaire,the Self-Rating Depression Scale,and WHOQOL-BREF Form. Results Among the 206 cases,the incidence of depression was 69.4%,and depression was negatively related to the quality of life（P = 0.000）. The multiple logistic regression analysis showed that the times of hospitalization（β=0.442,P=0.007）was a risk factor for depression,while the high education levels（β=-0.583,P=0.011）and the history of por-tal hypertension operation（β=-0.917,P=0.000）were the protective factors. Conclusion The incidence of depression in ad-vanced schistosomiasis patients is high,and it is influenced by various factors. Therefore,we should take corresponding interven-tions to reduce its occurrence.

关 键 词：晚期血吸虫病 抑郁 生活质量 影响因素 

分 类 号：R532.21[医药卫生—内科学]