利多卡因用于女性导尿术的荟萃分析  

Lidocaine for female patients during catheterization： A Meta-analysis

作　　者：杜少英[1] 杨楠[1] 陈玉芳[1] 窦昊颖[1] 

机构地区：[1]天津中医药大学护理学院,300193

出　　处：《中国实用护理杂志》2014年第17期18-22,共5页Chinese Journal of Practical Nursing

基　　金：天津市普通高等学校本科教学质量与教学改革研究计划重点项目资助（D03-1011）

摘　　要：目的系统评价利多卡因对女性患者导尿的影响。方法制定原始文献的纳入、排除标准和检索策略，计算机检索Cochrane图书馆、EMbase、PubMed、CBM、CNKI、VIP、WanFang等数据库。按Cochrane系统评价方法筛选文献并评价文献质量，采用RevMan5．0软件对所有数据进行Meta分析。结果共纳入11组随机对照试验研究。实验组，插管时使用利多卡因的患者737例；对照组，插管时使用生理盐水或安慰剂的患者711例。Meta分析结果显示，2种干预方法对女性患者导尿插管引起的疼痛、一次性插管成功率和全麻手术患者麻醉苏醒期躁动率有显著的影响，2组患者上述指标差异有统计学意义。结论女性患者导尿前尿道内注入利多卡因或用利多卡因乳膏（凝胶）润滑尿管可以降低插管时疼痛，提高一次性插管成功率，降低麻醉苏醒期躁动率。但上述结果尚需大样本、高质量的随机对照试验进一步验证。Objective To systematically evaluate the effects of lidocaine on female patients during urinary catheterization. Methods A literature search was conducted in following databases as the Cochrane Library, EMbase, PubMed, CBM, CNKI, VIP, and Wanfang data. All included RCTs were screened and assessed according to the standard of Cochrane systematic review. The data were analyzed by RevMan 5.0 software. Results A total of 11 RCTs were included, involving 737 patients in the experi- mental group, 666 patients in the control group. The results of Meta-analysis showed that there were signifi- cant differences between the two groups in the pain caused by intubation, one-time success rate of intuba- tion, and agitation rate in anesthesia recovery period. Conclusions Using lidocaine for female patients before catheterization may reduce the pain, increase the one-time success rate of intubation, and reduce agitation rate in anesthesia recovery period. The results still need to be confirmed by more high-quality and large-sample RCTs.

关 键 词：利多卡因 导尿术 META分析 随机对照试验 女性患者 

分 类 号：R472[医药卫生—护理学]