喷雾冷冻干燥对家蝇幼虫活性成分抗菌及抗炎活性影响  

Effects of Spray Freeze Drying on Antibacterial and Anti-inflammatory Activity of Housefly Larvae

作　　者：褚夫江[1,2] 刘文彬[1,2] 朱家勇[1,2] 

机构地区：[1]广东省生物活性药物研究重点实验室,广东广州510006 [2]广东药学院基础学院,广东广州510006

出　　处：《亚太传统医药》2014年第13期6-8,共3页Asia-Pacific Traditional Medicine

基　　金：国家自然科学基金项目(81274061);广东省战略性新兴产业核心技术攻关项目(2012A080800016);广东省医学科研基金项目(B2013189);广东省自然科学基金(S2013040014444);广东省高等学校学科与专业建设专项资金项目(2013LYM0045)

摘　　要：以人工饲养繁殖的家蝇(Musca)3龄幼虫为材料,探讨喷雾冷冻干燥对家蝇幼虫活性提取物抗菌及抗炎活性的影响。结果表明,经喷雾冷冻干燥处理的家蝇幼虫活性提取物对金黄色葡萄球菌和大肠埃希菌具有有效抑制作用;对LPS诱导的巨噬细胞炎症因子TNF-α和IL-6表达具有明显的抑制作用。Three instar larvae of housefly （Musca） which harvested by captive breeding was taken as raw materials. The effects of spray freeze drying on antibacterial and anti-inflammatory activity of housefly larvae were investigated. And the results showed thatthe extract of housefly larvae which was treated by spray freeze drying had the function of inhibiting the Staphylococcus aureus and Escherichia coli. And also the expression of TNF-α and IL-6 of macrophage which induced by LPS were inhibited when treated withthe extract of housefly larvae.

关 键 词：家蝇幼虫 喷雾冷冻干燥 冷冻干燥 抗菌 抗炎 

分 类 号：R282.74[医药卫生—中药学]