新型人工机械心脏瓣膜加速疲劳试验  

Accelerated Fatigue Test in Vitro of the New Mechanical Heart Valve

作　　者：武亮亮[1] 周丰[1] 孙鸿[1] 王进[1] 刘丽 黄楠[1] 

机构地区：[1]西南交通大学材料科学与工程学院,四川成都610031 [2]中国药品生物制品检定院医疗器械检定所,北京100050

出　　处：《西南交通大学学报》2014年第3期530-535,共6页Journal of Southwest Jiaotong University

基　　金：国家自然科学基金资助项目(20973134);国家高技术研究发展计划资助项目(2006AA02A139)

摘　　要：为评价新型瓣膜的开闭状态及疲劳特性,采用TH—2200型人工心瓣疲劳寿命测试仪对聚甲醛瓣叶的双叶心脏瓣膜和ON-X心脏瓣膜进行疲劳实验,并利用高速摄像机对瓣膜的开启与关闭情况进行跟踪,考察瓣膜的瞬时运动状态.实验结果发现,在体外加速疲劳实验中,新型双叶心脏瓣膜与ON-X心脏瓣膜在相同频率下具有相近的开启关闭周期,在瓣叶开启至极限位置时都有抖动产生,该瓣膜经3×108次疲劳测试后,瓣环无明显磨损,瓣叶转动灵活,心瓣正常工作.In order to evaluate the opening and closing states and fatigue properties of a new type of polyoxymethylene heart valve, accelerated fatigue tests were performed on the polyoxymethylene heart valve and an ON-X heart valve using the heart valve prostheses fatigue tester （TH-2200）. The opening and the closing positions of the leaflets were tracked using the high speed camera, and the instantaneous motion states of valves were investigated. The results show that the new heart valve had a similar opening-closing cycle at the same frequency with the ON-X heart valve in in vitro accelerated fatigue experiments, and the leaflets of both the valves would generate jitters when they opened to the limit position. After 3 × 10^8 cycles of fatigue tests, no obvious wear was found on the valve ring, the valve leaflets rotated flexibly, and the heart valve was working properly.

关 键 词：人工机械心脏瓣膜 疲劳测试 高速摄像机 

分 类 号：R318.11[医药卫生—生物医学工程]