吡唑啉酮衍生物及其金属配合物抗肿瘤研究进展  

Antitumor activities of pyrazolone derivatives and their metal complexes

作　　者：张思琪[1] 王路[1] 王振宇[1,2] 

机构地区：[1]哈尔滨工业大学生物化工系,黑龙江哈尔滨150090 [2]东北林业大学林学院,黑龙江哈尔滨150040

出　　处：《化学研究与应用》2014年第6期777-784,共8页Chemical Research and Application

基　　金：黑龙江省自然科学基金项目(C201037)资助

摘　　要：综述了吡唑啉酮衍生物及其金属配合物抗肿瘤生物活性国内外研究进展,主要包括吡唑啉酮衍生物及其金属配合物抗肿瘤生物活性,及其活性作用机制。展望了吡唑啉酮衍生物及其金属配合物抗肿瘤活性研究的发展方向。The researching progress of antitumor activities of the pyrazolone derivatives and their metal complexes at home and a-broad were reviewed,including their antitumor activities and antitumor mechanism. The development direction of pyrazolone deriva-tives and their metal complexes in antitumor activities researching had also been discussed.

关 键 词：吡唑啉酮 SCHIFF碱 金属配合物 抗肿瘤 

分 类 号：O614[理学—无机化学]