颅骨嗜酸性肉芽肿切除15例报告  

Resection of Skull Eosinophilic Granuloma: a Report of 15 Cases

作　　者：郑勇 成振林 王继超 

机构地区：[1]新疆自治区人民医院神经外科,乌鲁木齐830000 [2]石河子大学医学院,石河子832000

出　　处：《中国微创外科杂志》2014年第6期536-538,共3页Chinese Journal of Minimally Invasive Surgery

基　　金：吴阶平医学基金会临床科研专项资助基金(320670508061)

摘　　要：目的探讨颅骨嗜酸性肉芽肿（skull eosinophilic granuloma，SEG）手术治疗的效果。方法2011年1月～2012年9月对15例SEG，术中根据病变浸润、破坏颅骨骨质程度和病灶范围大小，分别采用病灶刮除和切除术，对于颅骨缺损直径〉3cm者，行一期颅骨修补。结果10例单纯手术切除，5例病灶刮除；7例行钛网修补。术后未辅助放、化疗。手术时间95～160min，（127．8±32．5）min；术中出血93～118ml，（105±13）ml。术后住院8～10d。术后病理：黄色肉芽肿，属于嗜酸性肉芽肿黄色肿块期。术后门诊随访1年，头颅CT、MRI检查均未见复发病灶。结论SEG经单纯病灶清除术后患者恢复良好，复发率低。单发、局限性病灶，无明显全身症状者，可不辅助放、化疗。Objective To investigate the clinical features and operation method of skull eosinophilic granuloma （SEG）. Methods A retrospective analysis of 15 cases of skull eosinophilic granuloma was made. During the operation, according to pathological destruction, degree and range of lesion size, curettage or hysterectomy was performed. For patients with skull defect diameter 〉 3 cm, cranioplasty was given. Results Totally 10 patients were treated with simple operation resection; 5 patients underwent curettage; 7 cases were given titanium mesh repair. No postoperative adjuvant radiotherapy or chemotherapy was adopted. Postoperative pathological diagnosis revealed xanthogranuloma. Fifteen patients were followed up for 1 year. Brain CT and MRI examination showed no recurrent lesions. Conclusions Simple debridement in the treatment of SEG bears rapid recovery and low recurrent rate. For those with single and localized lesion and without systematic symptoms, no adjuvant radiotherapy or chemotherapy is needed.

关 键 词：颅骨嗜酸性肉芽肿 切除 

分 类 号：R651.1[医药卫生—外科学]