GRE-T2*WI联合DWI在急性弥漫性轴索损伤中的诊断价值  

THE VALUE OF GRE-T28WI COMBINED WITH DWI IN THE ACUTE DIAGNOSIS OF DIFFUSE AXONAL INJURY

作　　者：王斌[1] 李军[1] 陈伟[1] 王金华[1] 

机构地区：[1]广东医学院附属厚街医院放射科,广东东莞523945

出　　处：《牡丹江医学院学报》2014年第3期25-28,共4页Journal of Mudanjiang Medical University

基　　金：东莞市医疗卫生科技计划项目(201210515023165)

摘　　要：目的:探讨磁共振梯度回波T2成像(GRE-T2*WI)联合扩散加权成像(DWI)在急性弥漫性轴索损伤(DAI)中的诊断价值。方法:回顾性分析38例急性弥漫性轴索损伤(DAI)患者的头颅MRI检查,比较MRI各序列间的检测灵敏度,并将检出的病灶数与患者入院格拉斯哥昏迷评分(GCS)行相关性分析。结果:T1WI共检出DAI病灶49个,T2WI检出78个、FLAIR检出139个,GRE-T2*WI检出142个,DWI检出212个,GRE-T2*WI联合DWI检出245个。DWI对非出血性DAI病灶的检出率最高,与其它序列的差异有统计学意义(p<0.05)。GRE-T2*WI对出血性DAI病灶的检出率最高,与其它序列检出率相比有统计学差异(p<0.05)。联合GRE-T2*WI及DWI两种技术对DAI病灶的检出率均显著高于单独应用DWI(p<0.05)或GRE-T2*WI(p<0.05)。联合GRE-T2*WI及DWI两种技术检出的病灶数目与患者入院GCS呈高度负相关(r=-0.796,P<0.01)。结论:GRE-T2*WI和DWI序列联合应用大大提高DAI病灶的检出率,为临床早期诊断提供更加可靠地影像学依据,应作为MRI检查DAI的常规序列。Objective：To investigate the value of T2＊weighted gradient -recalled-echo（GRE-T2＊WI） and diffusion weighted imaging（DWI） in diagnosis of acute diffuse axonal injury （DAI）.Methods：38 acute DAI patients underwent MRI sequence examina- 〈br〉 tion.The sensitivity of DWI , GRE-T2＊WI and conventional MRI sequence in diagnosis of DAI was compared .The correlation be-tween the number of lesions and initial Glasgow coma score （GCS） was analyzed.Results：The number of lesions detected by T1WI, T2WI, FLAIR, GRE-T2＊WI, DWI and combination GRE-T2＊WI with DWI was 49, 78,139,142,212, and 241 respectively.The detected number of non -hemorrhagic lesion on DWI was the highest and significantly higher than that on other sequences （p〈0.05）. The detected number of hemorrhagic lesion on GRE -T2＊WI was the highest and significantly higher than that on other sequence （ P〈0.05）.The number of lesions detected by combination GRE -T2＊WI with DWI was statistically more than that by DWI or GRE -T2＊WI （p〈0.05）.The number of lesions revealed by combination GRE -T2＊WI with DWI was negatively correlated with GCS （r=-0.796, P〈0.01）.Conclusion：Combination GRE-T2＊WI with DWI can improve detection ratio of DAI lesions by providing more image evidence for early clinical diagnosis , so GRE-T2＊WI and DWI should be the routine sequence in the MRI examination of DAI detection.

关 键 词：弥漫性轴索损伤 梯度回波T2＊成像 扩散加权成像 格拉斯哥昏迷评分 

分 类 号：R816.1[医药卫生—放射医学]